این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Pediatrics، جلد ۹، شماره ۵، صفحات ۱۳۴۴۵-۱۳۴۵۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Assessments of Serum 25-Hydroxy Cholecalciferol Levels in Neonates with Physiological Jaundice Candidate for Phototherapy
چکیده انگلیسی مقاله Background In newborns, jaundice is the most common ailment that necessitates medical treatment and hospital readmission. The aim of this study was to evaluate vitamin D3 status and investigate the role of phototherapy in the treatment of jaundice and the improvement of vitamin D3 status in neonates with physiological jaundice. Materials and Methods: This prospective research included 50 full-term neonates with physiological hyperbilirubinemia who were phototherapy candidates. They came from Egypt's Qena University Hospitals' Neonatal Intensive Care Units. Colorimetric assays of albumin and ionized calcium, as well as daily serum bilirubin and an ELISA assay of vitamin D3 were performed on the included cases before and 5 days after phototherapy, in addition to clinical assessments. Results: The findings revealed a high prevalence of vitamin D3 deficiency (96.7%), and a lower frequency of optimal and insufficient vitamin D3 status (3.3%) with lack of optimal vitamin D3 status among cases. Post-phototherapy total, direct, and indirect bilirubin levels were significantly lower than pre-therapy levels, with substantial improvement in vitamin D3 status (p < 0.05 for all). Furthermore, both serum total bilirubin (r=-0.703, p < 0.001) and serum indirect bilirubin (r=-0.710, p < 0.001) had significantly negative associations with vitamin D3 serum levels. Conclusion Without vitamin D3 supplementation, neonates with low vitamin D and physiological jaundice who were received phototherapy had considerably improved vitamin D status 5 days later.
کلیدواژه‌های انگلیسی مقاله Egypt, Neonatal hyperbilirubinemia, Physiological jaundice, Vitamin D3
نویسندگان مقاله | Nagwan I. Rashwan
Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.


| Ahmed El-Abd Ahmed
Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.


| Mohammed H. Hassan
Department of Medical Biochemistry, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.


| Faten Bakheet Taqi
Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.


| Mohamed Elsayed Mohamed Ahmed
Chemistry Department, Faculty of Science, Sohag University, Sohag, Egypt & Analytical Biochemistry Diploma, Chemistry Department, Faculty of Science, Menoufia University, Menoufia, Egypt.


| Ali Helmi Bakri
Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, 83523, Egypt.
نشانی اینترنتی https://ijp.mums.ac.ir/article_17774.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات