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Journal of Medical Microbiology and Infectious Diseases، جلد ۹، شماره ۴، صفحات ۲۲۵-۲۲۹
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عنوان انگلیسی Tocilizumab in Post Hematopoietic Stem Cell Transplant COVID-19: A Pediatric Case Report
چکیده انگلیسی مقاله Hematopoietic stem cell transplantation (HSCT) severely undermines the recipients' immune status and makes them prone to complications following viral infection. Here, we report a 3-year-old boy with mucopolysaccharidosis type VI who acquired SARS-CoV-2 infection after HSCT. The boy was diagnosed with SARS-CoV-2 during the post-transplant period (19 days after HSCT) when dealing with acute graft versus host disease (GVHD). He was successfully treated with remdesivir and tocilizumab and recovered. Well-timed treatment with tocilizumab might reduce the risk of invasive mechanical ventilation and death in patients with severe COVID-19 pneumonia in the early post HSCT period.
کلیدواژه‌های انگلیسی مقاله Post Hematopoietic Stem Cell Transplantation, COVID-19, Mucopolysaccharidosis
نویسندگان مقاله | Tahereh Rostami
Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Neda Alijani
Department of Infectious Diseases, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Azadeh Kiumarsi
Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Soroush Rad
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Seied Amirhosein Mirhoseini
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Mohammadreza Rostami
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Amir Hesabi
Department of Pediatric Cell Therapy, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Seyed Ali Mousavi
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Seied Asadollah Mousavi
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-361-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Host-pathogen interactions and susceptibility factors
نوع مقاله منتشر شده Case Report
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