این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Pediatrics، جلد ۲، شماره ۱، صفحات ۵۵-۶۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Synbiotic for Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial
چکیده انگلیسی مقاله Introduction Antibiotic- associated diarrhea is a common problem in pediatric population. There is growing interest in probiotics, probiotics and synbiotics for prevention of this complication because of their worldwide availability as dietary supplements. The aim of this study was to assess the efficacy of a synbiotic mixture in prevention of antibiotic- associated diarrhea.   Materials and Methods:  In this randomized controlled  trial,  218 patients ( 111 in the synbiotic and 107 in the placebo group) aged 6 months to 14 years with respiratory tract infection and/ or otitis media who needed antibiotic treatment in outpatient setting, were enrolled. They received 1 billion Colony Forming Unit of seven probiotics species plus Fructooligosaccharide in form of powder  or placebo ( matched for size, shape, and volume) for 7 days. Amoxicillin, Amoxicillin-clavalanic acid, cefixim and Azithromicin were the most common drugs used by physcicians Mothers recorded stool frequency and consistency daily for 7 days.   Results: We found no significant difference (P>0.05) in occurrence of diarrhea between synbiotic and placebo groups.   Conclusion: This synbiotic mixture did not appear to reduce antibiotic- associated diarrhea in children. Further studies are needed to investigate the potential benefits of Synbiotics in prevention of this disease.  
کلیدواژه‌های انگلیسی مقاله Synbiotic, Antibiotic-Associated Diarrhea, Prevention
نویسندگان مقاله | Seyed Ali Jafari
1Department of Pediatric Gastroenterology, Faculty of Medicine,Mashhad University of Medical Sciences, Mashhad, Iran


| Hamid Ahanchian
2Inflammation and Inflammatory Disorder Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mohammad Ali Kiani
Department of Pediatric Gastroenterology, Faculty of Medicine,Mashhad University of Medical Sciences, Mashhad, Iran.


| Ali Khakshour
Department of Pediatrics, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnourd, Iran.


| Zeinab Noorbakhsh
Department of Pediatric Gastroenterology, Faculty of Medicine,Mashhad University of Medical Sciences, Mashhad, Iran.


| Elham Zamani
Inflammation and Inflammatory Disorder Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Hamid Reza Kianifar
Department of Pediatric Gastroenterology, Faculty of Medicine,Mashhad University of Medical Sciences, Mashhad, Iran.
نشانی اینترنتی http://ijp.mums.ac.ir/article_2121.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات