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Iranian Journal of Neonatology، جلد ۱۳، شماره ۴، صفحات ۱۷-۲۰
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عنوان انگلیسی Comparison of Diagnostic Markers of Aortic Coarctation in Prenatal and Postnatal Echocardiography
چکیده انگلیسی مقاله Background: The prenatal diagnosis of coarctation of aorta (CoA) remains a major challenge, as the false-positive diagnosis is fairly common. The purpose of this study was to find some useful prenatal sonographic markers compatible with the postnatal diagnosis of CoA. Methods: The study included fetuses suspected of CoA in the second and third-trimester ultrasound tests. All cases were examined by fetal echocardiography at a single ultrasound clinic between 2019 and 2020. The proportion of right and left ventricular size was assessed and ductal/isthmus diameter ratio was measured. A comparison was drawn between the results of neonates with neonatal CoA and neonates without CoA. Results: Of 20 fetuses with suspected prenatal CoA, 3 (15%) had neonatal CoA. The mean ductal/isthmus ratio was significantly higher in the neonates with CoA (1.96 vs. 1.46; p< 0.001). The diagnostic power of ductal/isthmus ratio to detect CoA with a cut point of 1.53 had a sensitivity and specificity of 100% and 70.6%, respectively, a positive and negative predictive value of 37.5% and 100%, respectively, and an overall accuracy of 75%. Conclusion: The ductal/isthmus ratio diameter and ventricular disproportion are significant sonographic markers for the prenatal diagnosis of CoA, and the ductal/isthmus ratio has high sensitivity and specificity compared to postnatal findings.
کلیدواژه‌های انگلیسی مقاله Aortic coarctation, Fetal echocardiography, Prenatal diagnosis
نویسندگان مقاله | Narges Afzali
Department of Radiology, Faculty of Medicine, Mashhad Medical Sciences, Islamic Azad University, Mashhad, Iran


| hassan Birjandi
Department of Pediatric Heart Disease, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Abdolreza Malek
Department of Pediatric Rheumatology, Faculty of Medicine, Mashhad University of Med‌ical Sciences, Mashhad, Iran


| Homa Mohammadi
Faculty of Medicine, Mashhad Medical Sciences ,Islamic Azad University, Mashhad, Iran


| Mohammadreza Moradi
Radiology clinic of Nasl-e-Omid
نشانی اینترنتی https://ijn.mums.ac.ir/article_21455.html
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