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Iranian Journal of Medical Sciences، جلد ۴۷، شماره ۴، صفحات ۳۲۸-۳۳۷
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عنوان انگلیسی Trends in the Prevalence and Incidence of Opium Abuse and its Association with Coronary Artery Risk Factors in Adult Population in Iran: Findings from Kerman Coronary Artery Disease Risk Factors Study
چکیده انگلیسی مقاله Background: The prevalence of opium addiction in Iran is high probably due to the belief that opium has preventive effects against cardiovascular diseases. In the second phase of Kerman coronary artery disease risk factors study, the prevalence, incidence rate, and the association between opium use and other coronary artery disease risk factors (CADRFs) were assessed.Methods: In a cross-sectional study (2014-2018), 9996 inhabitants of Kerman, southeastern Iran, aged 15-80 years were recruited to the study. After taking fasting blood samples, the participants were examined or interviewed for demographic data and CADRFs, including opium use. The participants were categorized into “never”, “occasional”, and “dependent” users. The association between opium use and CADRFs was assessed with adjusted regression analysis (Stata v.11 software). Results: The overall prevalence of opium consumption was lower than that of five years earlier (P< 0.01). The prevalence was currently higher in men than women and decreased in men between the two phases (P< 0.001). There was a positive correlation between opium use and depression (P< 0.001), anxiety (P< 0.05), and a negative association with the level of physical activity (P< 0.001). The five-year incident rate of dependent and occasional opium use was 4.2 and 3.9 persons/100 person-years, respectively. The incidence of opium use was higher in diabetic, hypertensive, depressed, anxious, and obese subjects.Conclusion: The study did not demonstrate any protective effects of opium on CADRFs. Considering the higher rate of opium use in subjects with hypertension, diabetes, obesity, and psychological disorders, the health authorities should implement educational programs to warn and correct the unsafe belief.
کلیدواژه‌های انگلیسی مقاله Opium dependence, prevalence, Incidence, Coronary artery disease, Risk factors
نویسندگان مقاله Hamid Najafipour |
Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Mohammad Masoumi |
Cardiovascular Research Center, Department of Cardiology, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

Rahele Amirzadeh |
Social Determinants of Health Research Center, Institute of Future Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

Farzaneh Rostamzadeh |
Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

Rahim Foad |
Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Mitra Shadkam Farrokhi |
Gastroenterology and Hepathology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran

نشانی اینترنتی https://ijms.sums.ac.ir/article_48060_3fe66d09d4f7fa0f6df12862fb1279af.pdf
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