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International Journal of Radiation Research، جلد ۲۱، شماره ۳، صفحات ۳۶۹-۳۷۵
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عنوان انگلیسی Value of volume-rendering computed tomography for diagnosing different solitary pulmonary nodules and invasion depth in lung adenocarcinoma
چکیده انگلیسی مقاله Background: We aimed to analyze the value of volume rendering (VR) in diagnosing different solitary pulmonary nodules (SPNs) with diameter less than 1.0 cm and assessing invasion depth in lung adenocarcinoma. Materials and Methods: In total, 908 patients with SPN that was confirmed by postoperative pathology were included, followed by an analysis of the imaging characteristics (including microvascular sign, vascular convergence, lobulation, and spiculation) of malignant and benign SPN based on VR. Moreover, the detection rates of imaging signs of three types of malignant SPNs (pure ground grass nodule, pGGN; part-solid nodule; and solid nodule) classified by SPN density and three invasion depths of adenocarcinoma (pre-invasion lesion, PIL; micro invasive adenocarcinoma, MIA; and invasive adenocarcinoma, IAC) were also analyzed. Results: The microvascular sign detection rate was higher while vascular convergence and spiculation detection rates were lower in malignant SPN than in benign SPN. The microvascular sign possessed high sensitivity (82%) and specificity (72%) in predicting malignant and benign SPNs. The microvascular sign detection rate decreased while vascular convergence, lobulation, and spiculation detection increased with the rising density of malignant SPN. Furthermore, the detection rates of the four imaging signs all increased with the adenocarcinoma invasion depth. Microvascular sign showed good detecting ability in low density SPNs pGGN (81.8%), part-solid nodules (95.8%), and in all three invasion depths of adenocarcinoma (PIL [68.2%], MIS [95.3%], and IAC [87.2%]). Conclusion: These imaging features distinguished by VR exhibited an excellent differential diagnostic ability of various SPNs as well as invasion depth of lung adenocarcinoma.
کلیدواژه‌های انگلیسی مقاله Breast cancer, radiotherapy, lymphocytes, chromosomal aberration, bioindicator.
نویسندگان مقاله | J. Liu
Department of Medicine, Minhang Hospital, Fudan University, Shanghai 201199, China


| J. Liu
Department of Medicine, Minhang Hospital, Fudan University, Shanghai 201199, China


| J. Zhou
Department of Anesthesiology, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China


| L. Zhang
Department of Critical Care Medicine, Minhang Hospital, Fudan University, Shanghai 201199, China


| Amir Hosein Hadidi Zavareh
Department of Biology, North Tehran Branch, Islamic Azad University, Tehran, Iran
نشانی اینترنتی http://ijrr.com/browse.php?a_code=A-10-1-1054&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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