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The Journal of Tehran University Heart Center، جلد ۱۸، شماره ۲، صفحات ۱۲۹-۱۳۵
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عنوان انگلیسی Association of the Cardiovascular Risk Factors and High Risk Features in Myocardial Perfusion Imaging: A Multicenter Study
چکیده انگلیسی مقاله Background: Myocardial perfusion imaging (MPI) is a non-invasive method with acceptable sensitivity and specificity in diagnosing coronary artery disease (CAD) in moderate-risk patients, including patients with CAD risk factors. Methods: A cross-sectional and prospective study was conducted from April 2020 to March 2023 at Chamran and Tehran heart center hospitals. 4886 patients were included in this study. A questionnaire including anthropometric and demographic variables, CAD risk factors, and MPI findings was designed. Results: 2179 patients (44.6%) had an abnormal MPI. Patients with abnormal MPI were significantly older than patients with normal MPI. High-age [OR 1.64 (95% CI 1.2–1.72), P< 0.001], diabetes mellitus (DM) (OR 1.36 (95% CI 1.1–1.48), P=0.012), hypertension (HTN) [OR 1.24 (95% CI 1.04–1.37), P=0.032], and dyslipidemia (DLP) [OR 1.54 (95% CI 1.25–1.8), P< 0.001] were associated with abnormal MPI, independently. The higher of  number of CAD risk factors in a patient, the higher the probability of an abnormal MPI; Thus, in people without or at most one risk factor and in people with 8 CAD risk factors the likelihood of an abnormal MPI is 3.7% and 76.2%, respectively. Frequency of left ventricular dilation and prominent right ventricular in patients with high age (P< 0.001 and P=0.043, respectively), DLP (P< 0.001 and P=0.007, respectively), DM (P< 0.001 and P< 0.001), and HTN (P=0.048 and P=0.057, respectively) is significantly more. Conclusion: People with CAD risk factors, especially older people, and patients with DM, HTN, and DLP, should be given more attention for evaluation of CAD than other people by using MPI.
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نویسندگان مقاله | Hamid Khederlou
Tehran University of Medical Sciences


| Amirali Mohammadi
Zanjan university of Medical sciences


| Maryam Tajik
Tehran University of Medical Sciences


| Mohamad Kazemshiroodi
Iran University of Medical Sciences
نشانی اینترنتی https://jthc.tums.ac.ir/index.php/jthc/article/view/1854
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