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Medical Journal of Islamic Republic of Iran، جلد ۳۰، شماره ۱، صفحات ۸۷۱-۸۷۹
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عنوان انگلیسی A comparison of pattern of psychiatric symptoms in inpatients with bipolar disorder type one with & without methamphetamine use
چکیده انگلیسی مقاله Background: Iran is facing an outbreak of methamphetamine-induced disorders and frequent use of these substances in patients with bipolar disorder. Using or intoxication of methamphetamine in patients with bipolar I disorder may alter the patient's clinical profile; however there is limited studies about impact of methamphetamine on clinical manifestation of bipolar disorders. This study aimed to compare psychiatric symptoms in patients with bipolar I disorder with and without concomitant use of methamphetamine. Methods: In a cross-sectional study, psychiatric symptoms of bipolar I disorder in patients with (Meth+) and without (Meth-) methamphetamine use was evaluated. A number of 57 participants with Meth + and 50 subjects with Meth- were recruited. The clinical picture of bipolar disorder was investigated by Young Mania Rating Scale (YMRS), 17-item Hamilton Depressive Rating Scale (HDRS-17) and the Scale for Assessment of Positive Symptoms (SAPS). Statistical comparisons were performed using the T-test for independent samples and Mann-Whitney test. Results: There was no statistically significant difference between two groups regarding age, duration of illness and hospitalizations. However, male participants were significantly higher in Meth+ group than in Meth- one (p< 0.001). The mean (± SD) scores in the two groups of Meth+ and Meth- for YMRS, HDRS, and SAPS were 31.3 (±1.3) and 34.0 (±1.2), 13.7 (±0.7) and 13.5±(0.5), and 50.0 (±1.9) and 48.0 (±2.1), respectively, which were not statistically significant (p< 0.05). Conclusion: There was no significant difference in the overall clinical manifestation of bipolar I disorder in patients with and without methamphetamine use. However, in some symptomatology domains, there were some differences between the two groups.
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نویسندگان مقاله الهام گوران اوریمی | elham gouran ourimi
department of psychiatry, iran university of medical science, tehran, iran.


امیر شعبانی | amir shabani
bipolar disorders research group, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

کاوه علوی | kaveh alavi
mental health research center, bipolar disorders research group, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Mental Health Research Center

محمدرضا نجارزادگان | mohammad reza najarzadegan
department of psychiatry, iran university of medical science, tehran, iran.


فاطمه سادات میرفاضلی | fatemehsadat mirfazeli
department of psychiatry, iran university of medical science, tehran, iran.
نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-1054&slc_lang=en&sid=en
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