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JCR 2016
جستجوی مقالات
پنجشنبه 30 بهمن 1404
Dental Research Journal
، جلد ۲۰، شماره ۱۱، صفحات ۰-۰
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عنوان انگلیسی
Effect of local injection of injectable platelet‑rich fibrin on bone remodeling during orthodontic tooth movement in dogs
چکیده انگلیسی مقاله
Background: This study aimed to assess the effect of local injection of injectable platelet‑rich fibrin (i‑PRF) on bone remodeling during orthodontic tooth movement in dogs. Materials and Methods: In this animal study, the maxillary first premolars of four adult male mixed‑breed dogs were bilaterally extracted, and a nickel–titanium closed coil spring with 150 g force was placed between the canine and second premolar teeth. One quadrant of the maxilla was randomly selected as the test quadrant, and 0.5 cc i‑PRF was injected into the periodontal ligament (PDL) around the second premolar at 1, 21, and 42 days. The other quadrant served as the control group and received saline injections. The dogs were sacrificed after 63 days, histological sections were prepared, and changes in bone remodeling were assessed by comparing the percentage of osteogenesis and number of osteoblasts and osteoclasts between the two groups by the Wilcoxon and Mann–Whitney U‑tests (α = 0.05). Results: The percentage of osteogenesis (16.0% ± 4.96% in i‑PRF and 13.5% ± 4.43% in the control), the percentage of newly formed lamellar bone (10.25% ± 2.87% in i‑PRF and 8.75% ± 2.36% in the control), the percentage of woven bone (5.75% ± 2.21% in i‑PRF and 4.75% ± 2.36% in the control), the number of osteoblasts (15.0 ± 3.46 in i‑PRF and 11.75 ± 2.36 in the control), and the number of osteoclasts (11.25 ± 4.34 in i‑PRF and 6.25 ± 2.62 in the control) were not significantly different between the two groups (P > 0.05). Conclusion: PDL injection of i‑PRF around the second premolars of dogs under orthodontic force had no significant effect on bone remodeling. Key Words: Bone remodeling, platelet‑rich fibrin, tooth movement techniques Highlight masoud feizbakhsh : Pubmed , Google Scholar
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
| Atefeh Tabibi
| Masood Feizbakhs
| Nasim Esnaashari
| Seyed Mohammad Razavi
نشانی اینترنتی
http://drj.mui.ac.ir/index.php/drj/article/view/2532
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