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International Journal of Nanoscience and Nanotechnology (IJNN)، جلد ۱۹، شماره ۲، صفحات ۷۷-۸۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Screening Assessment of the Potential ‎Hazard of Nanomaterials using a Bull ‎Sperm
چکیده انگلیسی مقاله    This paper studied a potential hazard of titanium dioxide nanomaterials in the primary sreening methods on the sample of bull sperm. A method for stabilizing metal nanopowders and their derivatives for biomedical studies is proposed. It was found that the complex of titanium dioxide doped with silver (Ag-TiO2) and nanopowder of titanium dioxide (TiO2) at concentrations of 3 mg/ml initiate pathological changes in the bull sperm: the release of phospholipids as a result of the destruction of membranes and morphological abnormalities (abnormalities of the head, middle part, and tail, as well as the absence of acrosome, etc). The pathological effect of Ag-TiO2 nanocomposite was more pronounced. Doping with silver can increase the toxicity of nanotitanium dioxide, which requires further in-depth experimental studies using different concentrations by in vivo and in vitro methods.
کلیدواژه‌های انگلیسی مقاله Bull Sperm,Nanomaterials,Screening,Titanium dioxide.‎
نویسندگان مقاله O. Demetska |
Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine

O. Beliuha |
State Institution «Kundiiev Institute of Occupational Health of the National Academy of ‎Medical Sciences of Ukraine», Kyiv, Ukraine

V. Movchan |
State Institution «Kundiiev Institute of Occupational Health of the National Academy of ‎Medical Sciences of Ukraine», Kyiv, Ukraine

M. Didenko |
State Institution «Kundiiev Institute of Occupational Health of the National Academy of ‎Medical Sciences of Ukraine», Kyiv, Ukraine

V. Riabovol |
Bogomolets National Medical University, Kyiv, Ukraine

T. Patyka |
State Institution «Kundiiev Institute of Occupational Health of the National Academy of ‎Medical Sciences of Ukraine», Kyiv, Ukraine

V. Tsapko |
State Institution «Kundiiev Institute of Occupational Health of the National Academy of ‎Medical Sciences of Ukraine», Kyiv, Ukraine

A. Balia |
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan

نشانی اینترنتی https://www.ijnnonline.net/article_705088_ec59f07c180f86a9a27825661fceea7d.pdf
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