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Acta Medica Iranica، جلد ۲۰۱۰، شماره ۱۰، صفحات ۳۰۰-۳۰۳
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عنوان انگلیسی Serum Leptin Concentrations during the Menstrual Cycle in Iranian Healthy Women
چکیده انگلیسی مقاله Leptin, a circulating 16-kd polypeptide consisting of 167 amino acids, appears to be involved in the body weight homeostasis. Moreover leptin plays an important role for the reproductive system, early embryogenesis, and fat metabolism during pregnancy and puberty. Significant correlations have been found between leptin and sexual hormones, which is a cytokine and has hormonal properties. The aim of this study was to determine serum leptin levels during the menstrual cycle, and the association between serum leptin and reproductive hormones in young, healthy Iranian women. 42 healthy women volunteered for the study. They all had regular menstrual cycles, with cycle length varying between 26 and 32 days. None of them used oral contraceptives. All were of normal weight, with body mass index ( BMI) < 25 Kg/m2. Fasting blood samples were collected during the follicular phase, mid cycle and luteal phase of the menstrual cycle. FSH and LH were measured with coated tube immunoradiometric assay. Estrogen and progesterone were measured using antibody -coated tubes. Serum Leptin concentration were measured by Leptin (sandwich) ELISA. In menstruating women, serum leptin increased from 13.15+/-1.60 ng/ml in the early follicular phase to 16.57+/-1.68 ng/ml (P
کلیدواژه‌های انگلیسی مقاله Leptin, Menstrual cycle, Iranian women
نویسندگان مقاله ناهید عین اللهی | nahid einollahi
department of medical laboratory sciences, school of allied health medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نسرین دشتی | nasrin dashti
department of medical laboratory sciences, school of allied health medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فریبا نباتچیان | fariba nabatchian
department of medical laboratory sciences, school of allied health medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/4052
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Articles
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