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Iranian Journal of Otorhinolaryngology، جلد ۲۹، شماره ۱، صفحات ۲۹-۳۳
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عنوان انگلیسی Vitamin D Levels in Children with Adenotonsillar Hypertrophy and Otitis Media with Effusion
چکیده انگلیسی مقاله Introduction:Vitamin D has been suggested to play a considerable role in the function of the immune system in various infectious, inflammatory, and autoimmune conditions. Otitis media with effusion (OME), defined as the presence of non-purulent fluid within the middle ear without signs or symptoms of suppurative otitis media, has a number of inflammatory predisposing factors. This study was designed to explore the association between vitamin D deficiency and OME.Materials and Methods:In this cross-sectional study, 74 children aged 2–7 years with an obstructive indication for adenotonsillectomy were included. Patients were divided into two groups based on the need for ventilation tube insertion for OME. Thirty-two children were enrolled in the OME group and 42 in the control group. The mean vitamin D level was compared between the two groups.Results:Mean vitamin D concentration in all patients was 11.96±5.85 ng/ml (9.79±4.36 ng/ml in the OME group and 13.61±6.33 ng/ml in the control group; P=0.003). There was also a significant difference in levels of vitamin D in patients referred in winter (9.0±2.94 ng/ml) compared with the summer (19.85±4.21 ng/ml; P=0.001). Data analyzed based on the season in which the patients were referred showed no significant difference between the OME and the control group.Conclusion:Although our results showed lower serum levels of vitamin D in OME patients, the difference was not significant when seasons were taken into consideration. Therefore, the season is an important confounding factor in any research related to vitamin D due to the effect of sun-induced vitamin D.
کلیدواژه‌های انگلیسی مقاله Adenoids, Child, Vitamin D, Otitis Media, Seasons
نویسندگان مقاله علی محمد اصغری | ali mohamad asghari
skull base research center, ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

زهره باقری | zohreh bagheri
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

مریم جالسی | maryam jalesi
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

محمد مهدی سالم | mohamad mehdi salem
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

الهه امینی | elaheh amini
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

سهند قلعه باقی | sahand ghale baghi
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

سپیده بختی | sepideh bakhti
ent and head amp;amp; neck research center, hazrat rasoul akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

نشانی اینترنتی http://ijorl.mums.ac.ir/article_8066.html
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