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Iranian Journal of Blood and Cancer، جلد ۱۶، شماره ۲، صفحات ۷۰-۸۳
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Molecular Pathways of Gliomas Involving RNA-Binding Protein Dynamics
چکیده انگلیسی مقاله
Gliomas are malignant brain tumors with complicated molecular changes contributing to their aggressiveness and limited treatment choices. RNA-binding proteins are important in post-transcriptional regulation, altering gene expression and impacting glioma formation. In this review article, we will deliberate different molecular pathways of gliomas in which RNA-binding proteins are involved. Studies reveal that a few years ago, RNA-binding proteins had a causative effect on various cancer types such as leukemia, glioblastoma, intestinal, renal, etc. RNA-binding proteins have surfaced as key players in regulating post-transcriptional processes. So, we will discuss in this article Maintaining Glioma Cells Growth, RNA-binding proteins mutations, interacting with deubiquitinating enzymes, RBP Methylation Activates Oncogenic Pathways and RNA-binding proteins in glioma subtypes, highlighting their role in tumorigenesis, invasion, angiogenesis, and therapeutic resistance.
کلیدواژه‌های انگلیسی مقاله RNA-binding proteins, Gliomas, post-transcriptional regulation, Oncogenetic pathways, RBP Methylation
نویسندگان مقاله | Saman Batool
Gomal Centre of Biochemistry and Biotechnology, Gomal University, D.I.Khan, Pakistan.


| Hamza Tanveer
Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, Pakistan


| Faisal Naeem
Department OF Forensic Medicine and Toxicology, Post Graduate Medical Institute, Lahore, Pakistan


| Asma Sarfaraz
Shifa Tameer-e-Millat University of Pharmaceutical Sciences, Islamabad, Pakistan
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-1068-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Adults Hematology & Oncology
نوع مقاله منتشر شده مقاله مروری
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