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Iranian Journal of Nuclear Medicine، جلد ۲۳، شماره ۲، صفحات ۱۲۸-۱۳۳
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عنوان انگلیسی 18F-FDG PET/CT usefulness vs Tc99m-Tetrofosmin in the assessment of malignant brain gliomas: Report of two cases
چکیده انگلیسی مقاله Gliomas account for almost 80% of primary malignant brain tumors in adults. Magnetic Resonance imaging (MRI) is still the gold standard for diagnosis of brain tumors and brain 99mTc-tetrofosmin Single Photon Emission Computed Tomography (99mTc-tetrofosmin-SPECT) has been established as a useful tool for their evaluation. Fluorine-18–2-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) provides non-invasive information for staging, clinical assessment and prognosis of glial tumors. We report 2 cases of patients with brain lesions described on MRI suspected for malignancy, however 99mTc-tetrofosmin-SPECT that didn’t show any lesion, 18F-FDG PET/CT revealed radiotracer uptake that supported the hypothesis of malignant gliomas, confirmed later by biopsy. Our cases confirm 18F-FDG PET/CTmay be useful for differentiating common enhancing malignant brain tumors and is recommended when differential diagnoses are difficult to narrow using MRI and 99mTc-tetrofosmin-SPECT. 18F-FDG PET/CT can be used to characterize their aggressiveness and to detect a more feasible site for a stereotaxic biopsy. It yields supplementary non-invasive information to conventional imaging useful in the clinical decision-making.
کلیدواژه‌های انگلیسی مقاله Malignant gliomas,Risk stratification,18F-FDG PET/CT
نویسندگان مقاله corinna altini |
nuclear medicine unit, university of bari “aldo moro”, bari, italy

artor niccoli asabella | artor niccoli
nuclear medicine unit, university of bari “aldo moro”, bari, italy

domenico rubini |
nuclear medicine unit, university of bari “aldo moro”, bari, italy

giuseppe ingravallo |
pathological anatomy unit, university of bari “aldo moro”, bari, italy

adriano nicoletti |
nuclear medicine unit, university of bari “aldo moro”, bari, italy

giuseppe rubini |
nuclear medicine unit, university of bari “aldo moro”, bari, italy

نشانی اینترنتی http://irjnm.tums.ac.ir/article_13279_4f248198a2e5628635b90167482ec58b.pdf
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