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Iranian Journal of Nuclear Medicine، جلد ۲۱، شماره ۱، صفحات ۷-۱۲
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عنوان انگلیسی Gated myocardial perfusion SPECT in patients with left bundle block but having low probability of coronary artery disease; as compared to the patients with normal electrocardiogram
چکیده انگلیسی مقاله Introduction: We aimed to investigate of effect of left bundle branch block (LBBB) on perfusion and functional parameters in dipyridamole Tc99m-MIBI gated myocardial perfusion SPECT which may be helpful in interpretation of myocardial perfusion imaging. Methods: We studied 70 patients with low pre-test probability of coronary artery disease in two groups: 35 patients with LBBB and 35 subjects with normal ECG. Both groups underwent two-day dipyridamole stress–rest Tc99m-MIBI GSPECT. Results: From 35 patients with LBBB, 6, 12, and 3 patients had reversible, fixed and partially reversible defects respectively. In 35 patients with LBBB, 8 (22.9%), 6(17.1%) 15( 42.9%) and 10 (28.6%) patients had perfusion defects in the apicoseptal, mid-anterior segments , mid-anteroseptal and mid-inferoseptal segments respectively. There was significant difference in TID ratio between two groups: LBBB group: 1.07±0.21 and control group: 0.96±0.14 (P=0.01). There was a significant difference in end systolic volume and ejection fraction between LBBB patients group and control group, while no significant difference was noticed in end-diastolic volume. Nineteen, 14 and 2 from 35 patients with LBBB had normal LV wall motion, paradoxical septal wall motion, and septal hypokinesia respectively. Conclusion: False positive septal, anterior and apicoseptal perfusion abnormalities are frequently seen on Tc99m-MIBI GSPECT, in patients with LBBB without CAD. Moreover reversible defects are frequently seen with Tc99m-MIBI. Even Tc99-MIBI and vasodilator stress do not increase diagnostic accuracy to clinically useful levels. Lower systolic performance and higher TID ratio could be seen in these patients.
کلیدواژه‌های انگلیسی مقاله LBBB,Gated SPECT,Myocardial perfusion,TID,Wall motion
نویسندگان مقاله سید هاشم دانش ثانی | seyed hashem danesh sani
department of cardiovascular diseases, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

سید رسول زکوی | seyed rasoul
nuclear medicine research center, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

رامین صادقی |
nuclear medicine research center, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

منصوره فاطمی |
department of cardiovascular diseases, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

مریم ترابیان کاخکی | torabian kakhki
faculty of veterinary medicine, ferdowsi university of mashhad, mshhad, iran
سازمان اصلی تایید شده: دانشگاه فردوسی (Ferdowsi university)

وحید رضا دباغ کاخکی | vahid reza dabbagh kakhki
nuclear medicine research center, ghaem hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://irjnm.tums.ac.ir/article_2560_15c6a73cdf256513ee894f5a77dbc636.pdf
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