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Iranian Journal of Nuclear Medicine، جلد ۱۸، شماره ۱، صفحات ۴۵-۵۱
عنوان فارسی
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عنوان انگلیسی Sensitivity of gallium scintigraphy for evaluation of recurrent lymphoma: Comparison of planar and SPECT imaging
چکیده انگلیسی مقاله Introduction: Although PET scanning using F-18[FDG] is considered the superior radiotracer for tumnor imaging, Gallium-67 is still in use for some malignancies such as lymphoma and hepatoma. One of the strategies to improve the diagnostic accuracy of Gallium is to perform SPECT which is reported to be more sensitive compared to planar imaging. In this study we compared the sensitivity of SPECT and planar imaging in patients suspicious of thoracic recurrent lymphoma. Methods: 129 patients with suspicious recurrent lymphoma of the thorax were included into the study. All patients received 10 mCi Gallium-67-citrate intravenously. Twenty four and 48 hours post injection whole body and thoracic SPECT imaging was performed. The final diagnosis of recurrence was achieved by combination of clinical and imaging findings or pathologic examination whenever possible. Results: The final diagnosis of 83 (64.3%) patients was recurrence of lymphoma in the thoracic area and the remainder 46 (35.7%) were in remission. The sensitivity of planar and SPECT imaging for diagnosis of recurrent lymphoma was 63% ([52-73%] with 95% confidence intervals) and 87% ([79-94%] with 95% confidence intervals), respectively. Conclusion: In our study, 20 patients with the final diagnosis of lymphoma recurrence in the thoracic area had negative planar despite positive SPECT imaging. This showed an increase of 24% in sensitivity of the scan (from 63% to 87%) by adding SPECT imaging to the procedure. Our recommendation is integrating SPECT modality into all gallium scintigraphy for lymphoma recurrence.
کلیدواژه‌های انگلیسی مقاله Gallium-67,Planar imaging,SPECT,Sensitivity,Lymphoma
نویسندگان مقاله رامین صادقی |
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

hosnoddin nabiev |
general practitioners, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

وحید رضا دباغ کاخکی | vahid reza dabbagh kakhki
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

مهدی مومن نژاد |
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

تکتم محمدی رعنا | mohammadi rana
general practitioners, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

سید رسول زکوی | seyed rasoul
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

کامران آریانا |
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://irjnm.tums.ac.ir/article_550_d1449792dd221e148c44eef06e4917f9.pdf
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