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Iranian Journal of Nuclear Medicine، جلد ۱۶، شماره ۲، صفحات ۲۳-۲۷
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عنوان انگلیسی The need for skin pen marking for sentinel lymph node biopsy: A comparative study
چکیده انگلیسی مقاله Introduction: There is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (I and II) breast cancer patients. Usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. In this study we evaluated this issue in our patients. Methods: 40 patients with the clinical diagnosis of early stage breast cancer (stage I or II) were included into the study. All patients received periareolar intradermal injections of 18.5 MBq Tc-99m antimony sulfide colloid 2-4 hours before the surgery and 2 ml patent blue V dye in a subdermal and periareolar fashion during surgery. The patients were divided randomly into two groups (20 patients in each group). In group I, the anterior and lateral locations of the sentinel lymph node were marked on the skin with an indelible ink. In group II, no skin marking was used. A sentinel node was defined as any blue node or any node with an ex vivo radioisotope count of twofold or greater than the axillary background. All patients underwent standard axillary lymph node dissection after sentinel node biopsy. Results: Mean age and tumor size were not significantly different between groups. SLN detection rate and number of detected SLNs were not significantly different either (P>0.05). Number of detected lymph nodes was 1.24±0.43 and 1.28±0.61 in group I and II of the patients, respectively. False negative rate (negative SLN and positive axillary nodes) for both groups were 0%. Conclusion: Although marking the location of the sentinel lymph node on the skin with an indelible ink can guide the surgeon during surgery, it can not increase the sentinel lymph node detection rate or improve the results of sentinel lymph node biopsy.
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نویسندگان مقاله رامین صادقی |
nuclear medicine department, imam reza hospital, imam reza hospital, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محمدناصر فرقانی | mohammad naser
surgery department, omid hospital, mashhad, iran.

سید رسول زکوی | seyed rasoul
nuclear medicine department, imam reza hospital, imam reza hospital, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

علی جنگجو |
surgery department, imam reza hospital, mashhad university of medical sciences, mashhad, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

غلامعلی شعبانی |
radioisotope division, nuclear research center, atomic energy organization of iran, tehran, iran,
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

وحید رضا دباغ کاخکی | vahid reza dabbagh kakhki
nuclear medicine department, imam reza hospital, imam reza hospital, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://irjnm.tums.ac.ir/article_512_f1ac41d507d864f6258fc09bc989057d.pdf
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