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Iranian Journal of Nuclear Medicine، جلد ۱۲، شماره ۱، صفحات ۴۹-۶۱

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عنوان انگلیسی Production, formulation, quality control and primary biological studies of [18F]KF for skeletal PET scanning [Persian]
چکیده انگلیسی مقاله [18F]KF, considered as a reference standard for positron emission tomography of the skeletal system, was produced by the bombardment of enriched water ([18O]H2O>95%) with high energy protons in NRCAM cyclotron. After the extraction of fluoride from enriched water as KF, and passing it through microbial filter and fine adjustment of acidity and osmolality, it was converted into an injectable form. Pre-clinical investigations and biological controls were performed to determine radioisotope distribution in laboratory rats, thus suitable information was gathered for imaging in humans. This radiopharmaceutical was proved to be quite safe and of high quality as a result of testing in laboratory rats.
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نویسندگان مقاله امیررضا جلیلیان | amir reza
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

محمد میرزایی |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

پژمان rowshanfarzad |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

محمدرضا انصاف | mohammad reza
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

علیرضا کریمیان |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

غلامرضا اصلانی |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

فرحناز معتمدی سده | motamedi sedeh
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

مهربان پولادی |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

بهروز شیرازی |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)

حسین آفریده |


سعید دانشوری |
cyclotron and nuclear medicine department, agricultural, medical and industrial research school, nuclear science and technology research institute, atomic energy organization of iran, karaj, iran
سازمان اصلی تایید شده: سازمان انرژی اتمی (Atomic energy organization)


نشانی اینترنتی http://irjnm.tums.ac.ir/article_439_0cc517d9f5495c872885b26a609a155b.pdf
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