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Iranian Journal of Blood and Cancer، جلد ۱۶، شماره ۳، صفحات ۵۵-۶۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Impact of SARS-CoV-2 on Oncogenesis: A Deep Dive into the COVID-19 and Cancer Nexus
چکیده انگلیسی مقاله
Background: The COVID-19 pandemic, triggered by the SARS-CoV-2 virus, has posed significant global health challenges, notably affecting individuals with pre-existing conditions like cancer. This review aims to provide an overview of current evidence regarding the bidirectional relationship between COVID-19 and cancer, focusing on potential mechanisms driving this association.
Search Strategy: A systematic search of the PubMed, Scopus, and Web of Science databases was conducted to identify studies published between January 2020 and March 2024. Articles were selected based on their relevance to the topic and adherence to rigorous methodological standards.
Results: Research indicates a complex interaction between COVID-19 and cancer, with clinical data highlighting variations in cancer diagnosis, prognosis, and treatment efficacy during SARS-CoV-2 infection. Mechanistic studies suggest that immune system dysregulation, chronic inflammation, and possible viral-induced cellular changes may contribute to cancer progression. Additionally, the pandemic has disrupted cancer care, causing delays in diagnosis and treatment, exacerbating existing healthcare disparities, and negatively affecting patient outcomes.
Conclusions: SARS-CoV-2 impacts cancer progression through a combination of direct and indirect mechanisms. Future studies should focus on identifying vulnerable cancer patient populations, clarifying molecular pathways connecting COVID-19 and cancer progression, and developing tailored therapeutic approaches to mitigate these risks.
کلیدواژه‌های انگلیسی مقاله SARS-CoV-2, COVID-19, Cancer
نویسندگان مقاله | Muhammad Waqas
Division of Science and Technology, Department of Zoology, University of Education, Lahore, Pakistan.


| Razia Bashir
Division of Science and Technology, Department of Zoology, University of Education, Lahore, Pakistan.


| Lea Nohra
Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.


| Stephen Feranmi Adeyemo
Division of Medical Artificial Intelligence, Helix Biogen Institute, Ogbomosho, Oyo State, Nigeria, Nigeria.


| Duru Confidence
Department of Veterinary Biochemistry and Physiology, University of Abuja, Nigeria.


| Muhammad Tayyab
Division of Science and Technology, Department of Chemistry, University of Education, Lahore, Pakistan.


| Sami ur Rahman
Division of Science and Technology, Department of Zoology, University of Education, Lahore, Pakistan.
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-1151-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Infectious Diseases
نوع مقاله منتشر شده مقاله مروری
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