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Journal of Medical Microbiology and Infectious Diseases، جلد ۱۰، شماره ۴، صفحات ۱۵۳-۱۵۶
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عنوان انگلیسی Parameters of Coagulation in COVID-19 Patients: A Correlation with Clinical Severity
چکیده انگلیسی مقاله Introduction: COVID-19 infection can be complicated by coagulation derangement and a high risk of thromboembolic episodes. Our study aimed to investigate coagulation parameters in COVID-19 patients and their correlation with clinical severity. Methods: We analyzed coagulation parameters PT, APTT, D-Dimer, and Fibrinogen in 98 RT-PCR-confirmed COVID-19 patients admitted to the Government Institute of Medical Sciences, Gautam Buddha Nagar, Uttar Pradesh, India. Results: This study involved 69 males (70.50%), and 29 (29.5%) were females. The mortality rate was 6.12% (n= 06). Forty-six patients (46.94%) had comorbidities. Thirty-four patients had elevated PT, and 7 had high APTT, whereas D-dimer and fibrinogen levels were raised in 68 and 61 patients, respectively. Among all four parameters, D-Dimer levels were significantly associated with disease severity. Conclusion: Derangement of D-dimer levels is significantly associated with disease severity in COVID-19 infection.
کلیدواژه‌های انگلیسی مقاله APTT, Coagulation, D-Dimer, Fibrinogen, PT, COVID-19
نویسندگان مقاله | Shalini Shukla
Government Institute of Medical Sciences, Gautam Buddha Nagar


| Kanchan Kamini
National Institute of Medical Sciences, Jaipur


| Bhumika Gupta
Homi Bhabha Cancer Hospital, Varanasi


| Shalini Bahadur
Government Institute of Medical Sciences, Gautam Buddha Nagar


| Shivani Kalhan
Government Institute of Medical Sciences, Gautam Buddha Nagar


| Madhuvan Gupta
Government Institute of Medical Sciences, Gautam Buddha Nagar
نشانی اینترنتی http://jommid.pasteur.ac.ir/browse.php?a_code=A-10-403-1&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Diagnostic/screening methods and protocols
نوع مقاله منتشر شده Original article
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