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Journal of Biostatistics and Epidemiology، جلد ۱۰، شماره ۱، صفحات ۱۹-۳۲
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عنوان انگلیسی The effects of hypocaloric, high-protein diets on cardiovascular risk factors and weight loss in obese adults: a systematic review
چکیده انگلیسی مقاله Abstract Background: This systematic review has been undertaken in order to assess the effects of hypocaloric, high-protein diets on weight loss and cardiovascular risk factors such as serum lipid levels in metabolically healthy obese adults. The primary outcomes measured include changes in pre- and post- diet mean BMI, LDL-C, HDL-C, TAG, and TC levels.  Method: Four databases including: Embase, MEDLINE (via PubMed), Cochrane and Web of Science were searched with no restrictions on language or publication period. Clinicaltrials.gov was also searched in order to identify unpublished or on-going studies. Results: Three of four studies included in this systematic review noted a significantly greater loss in pre- and post- diet mean BMI levels in the hypocaloric, high-protein diet group as compared to hypocaloric, non-high protein diets (control). Whilst pre- and post-diet mean LDL-C, HDL-C, TAG, and TC levels did not differ significantly among hypocaloric, high-protein and control diet groups. Conclusion: Hypocaloric, high-protein diets had an unclear effect on blood-lipid levels as compared to control. Weight loss however was significantly greater in the hypocaloric, high-protein group as compared to other hypocaloric, non-high-protein diet groups. 
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نویسندگان مقاله | Martin Lauran
GKT School of Medical Education, King’s College London, London, UK


| Ali Jafari
Farhikhtegan Hospital, Azad university of Medical Sciences, Tehran, Iran


| Kosar Ali
College of Medicine, University of Sulaimani, Sulaimani, Iraq


| Seyed Hosseini
TUMS
نشانی اینترنتی https://jbe.tums.ac.ir/index.php/jbe/article/view/1481
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