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The Journal of Tehran University Heart Center، جلد ۱۲، شماره ۱، صفحات ۲۳-۲۶
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عنوان انگلیسی Significance of Abnormal Myocardial Perfusion Scans in Candidates for Orthotopic Liver Transplantation
چکیده انگلیسی مقاله Background: The implications of cardiac risk stratification before orthotopic liver transplantation (OLT) are not well established. We studied the usefulness of myocardial perfusion imaging (MPI) in this scenario. Methods: MPI data of 24 patients (9 females), candidates of OLT, were collected. They underwent MPI as part of their preoperative risk assessment. MPIs were interpreted by 2 nuclear physicians, who had access to clinical data, scan, and semi-quantification results (i.e., quantitative perfusion single-photon emission tomography (SPECT) [QPS] and quantitative gated SPECT [QGS]). A 3rd nuclear physician, blinded to the clinical history of the subjects, re-reviewed the scans. The visual interpretations of MPI (i.e., normal vs. abnormal), ejection fraction, and transient ischemic dilation index derived from QPS and clinical and follow-up data were collected and analyzed. Results: The follow-up period was 231.0 ± 86.0 days. The MPIs were normal in 16 (66.7%) patients and abnormal in 8 (i.e., 5 mild [20.8%], 1 [4.2%] moderate, and 2 [8.3%] severe). Out of 4 patients who died during the follow-up, 1 had mild ischemia and 2 had severe ischemia. A patient who had a normal MPI died due to noncardiac reasons. A patient with abnormal MPI had 3-vessel disease on angiography. Out of the 5 patients who died or had significant coronary angiographic abnormalities, 4 had abnormal MPIs (negative predictive value = 93.8%; sensitivity = 80.0%) The MPIs of 4 patients without perioperative mortality or cardiac morbidity were abnormal (specificity = 78.9%). Conclusion: MPI seems to be remarkable in discriminating high-risk OLT patients preoperatively. 
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نویسندگان مقاله عاطفه اسماعیلی | atefe esmaili
research institute for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سعید farzanefar | saeed farzanefar
department of nuclear medicine, vali-asr hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا امامی اردکانی | alireza emami ardakani
research institute for nuclear medicine, shariati hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مهرشاد عباسی | mehrshad abbasi
department of nuclear medicine, vali-asr hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jthc.tums.ac.ir/index.php/jthc/article/view/674
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/65/article-65-349937.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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