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Medical Journal of Islamic Republic of Iran، جلد ۲۸، شماره ۱، صفحات ۶۴۶-۶۵۲

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عنوان انگلیسی Relationship between serum levels of fetuin-A with apo-A1, apo-B100, body composition and insulin resistance in patients with type 2 diabetes
چکیده انگلیسی مقاله Background :Some results exist on fetuin-A as marker for vascular disease in type 2diabetes. We examined the relationship between serum fetuin-A with some factors, in patients with type 2 diabetes mellitus (T2DM). Methods : From October 2012 to June 2013, a total of 131 T2DM patients were recruited and evaluated for various parameters including HOMA-IR, Apo-A1, Apo-B100, body fat percentage and waist circumference. Serum fetuin-A levels were measured by enzyme-linkedimmunosorbent assay (ELISA), and Serum glucose with a Cobas MIRA analyzer by enzymatic method. Apo-B100 and apo-A1 were measured by immunoturbidimetry with a Cobas MIRA analyzer. HOMA-IR was calculated by the following formula: [fasting insulin (uIU/mL) × fasting blood glucose (mmol/L)]/22.5. Results : The mean levels of HOMA-IR were significantly increased progressively across fetuin-A tertiles (pfor trend=0.04) in women but not men. Fetuin-A had just a significant positive correlation withApo- A1(r=0.22, p=0.02). Conclusion : This present study showed that levels of serum fetuin-A are significantly associated with insulin resistance in women with T2DM.
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نویسندگان مقاله فرزاد شیدفر | farzad shidfar
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center

میترا زراتی | mitra zarrati
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center

محمد ابراهیم خمسه | mohamad ebrahim khamseh
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center

ندا حقیقت | neda haghighat
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center

علی رستمی | ali rostami
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center

حمید ذوالفقاری | hamid zolfaghari
institute of endocrinology and metabolism research and training center, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
سازمان های دیگر: Institute of Endocrinology and Metabolism Research and Training Center


نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-732&slc_lang=en&sid=en
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