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International Journal of Pediatrics، جلد ۱۲، شماره Issue ۴ (In Progress)، صفحات ۱۸۷۰۰-۱۸۷۱۱
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عنوان انگلیسی Investigating the Frequency of Coagulation Abnormality in Hospitalized Children with Covid19: A Cross-Sectional Study
چکیده انگلیسی مقاله Background: Based on the findings of previous studies, patients with severe Covid-19 have a much greater occurrence of coagulation abnormalities. Additionally, individuals who get this novel virus are susceptible to developing disseminated intravascular coagulation. The present study aimed to investigate the frequency of coagulation disorders in children with covid-19 who were hospitalized in Bandar Abbas Children's Hospital during 2020-2021. Methods: This study was done retrospectively. The medical records of all children were checked with a definite diagnosis of Covid-19, based on positive PCR results. Age, gender and comorbidity status were obtained from the medical records of the patients. In addition, white blood cell count, blood platelet count, hemoglobin concentration, CRP, PT, PTT, INR, D-dimer and fibrinogen were checked. Data was analyzed using SPSS 22 software with a significance threshold of 0.05. Results: In this study 20.63% had coagulation abnormalities. The groups with and without coagulation disease exhibited a significant difference in the proportions of neutrophils and lymphocytes. Specifically, the coagulation disorder group had elevated levels of neutrophils and reduced levels of lymphocytes (P= 0.043, P= 0.041, respectively). The average D-dimer level and age in the group with coagulation disorder was significantly greater than those in the group without coagulation problem (P= 0.000, P=0.045). Conclusion: According to the findings of this research, 20.63% of children who were definitively diagnosed with covid-19 had coagulation abnormalities. Only the alterations in D-dimer, lymphocyte, and neutrophil levels were shown to be substantially associated with coagulation disorders in this investigation. Specifically, in the group with coagulation disorders, there was an elevation in neutrophil count and a decrease in lymphocyte count.
کلیدواژه‌های انگلیسی مقاله COVID-19, coagulation disorder, Children, D-dimer
نویسندگان مقاله | Arian Karimi Rouzbahani
USERN Office, Lorestan University of Medical Sciences, Khorramabad, Iran Student Research committee, Lorestan University of Medical Sciences, Khorramabad, Iran


| Samaneh Tahmasebi Ghorabi
Master Health Education, Ilam University of Medical Sciences, Ilam, Iran


| Maryam Mohammadian
Department of Pediatric, Clinical Research Development Center of Children Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.


| Maliheh Mohammad Zadeh
Department of Pediatrics, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran


| Zahra Goudarzi
Bachelor of Nursing Student, scientific Research of Committee, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran


| Mahmood Mallahi
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran


| Mohammad Ali Molavi
Department of Pediatric Oncology, pediatric Hospital, GolShahr, Bandar Abbas, Iran
نشانی اینترنتی https://ijp.mums.ac.ir/article_24763.html
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