این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
The Journal of Tehran University Heart Center، جلد ۷، شماره ۳، صفحات ۱۱۷-۱۲۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Pregnancy Outcome after Mechanical Mitral Valve Replacement: A Prospective Study
چکیده انگلیسی مقاله Background: Pregnant patients with mechanical heart valves require anticoagulation. The risk of bleeding and embryopathy associated with oral anticoagulants must be weighed against the risk of valve thrombosis. Methods: In this prospective study, undertaken between 1999 and 2009, 53 pregnancies (47 women with mechanical mitral valves; 29.8 ± 4.8 years old) were studied. Patients were divided into two groups: group I (n = 43) received Warfarin throughout the pregnancy, while group II (n = 10) received Heparin in the first trimester and then Warfarin until the 36th week. Results: Thirty-two (60.4%) pregnancies resulted in live births, whereas 18 (34%) abortions, 2 (3.8%) stillbirths, and one (1.9%) maternal death occurred. In group I, there were 26 (60.5%) live births, one (2.3%) stillbirth, and 15 (34.9%) abortions. In group II, there were 6 (60%) live births, one (10%) stillbirth, and 3 (30%) abortions. There were no significant differences between the two groups in terms of fetal outcome. Thirty-nine (90.7%) of the pregnancies in group I and 50% of those in group II (p value = 0.001) were without complications. There were no congenital malformations in the two groups. Conclusion: Fetal outcome was almost the same between the Warfarin and Heparin regimens. In maternal outcome, the W arfarin regimen is safer than Heparin.
کلیدواژه‌های انگلیسی مقاله Pregnancy • Heart valve prosthesis • Anticoagulants
نویسندگان مقاله نیلوفر سمیعی | niloufar samiei
heart valve disease research center, rajaei cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فهیمه کشفی | fahimeh kashfi
heart valve disease research center, rajaei cardiovascular medical and research center, tehranuniversity of medical sciences, tehran, iran. and reproductive epidemiology research center, royan institute, acecr, tehran, iran.

سازمان اصلی تایید شده: پژوهشگاه رویان (Royan institute)

amirjamshid خاموشی | amirjamshid khamoushi
heart valve disease research center, rajaei cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سعید حسینی | saeid hosseini
heart valve disease research center, rajaei cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا علیزاده قویدل | alireza alizadeh ghavidel
heart valve disease research center, rajaei cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

دکتر ربابه طاهری پناه | robabeh taheripanah
imam hossein hospital, shahid beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

یلدا mirmesdagh | yalda mirmesdagh
heart valve disease research center, rajaei cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jthc.tums.ac.ir/index.php/jthc/article/view/258
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