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The Journal of Tehran University Heart Center، جلد ۵، شماره ۱، صفحات ۱۴-۱۸
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عنوان انگلیسی Preliminary Study of Cardiovascular Manifestations and Cardiac Severity Scale in 58 Patients with Systemic Sclerosis in Iran Using the Medsger Scale
چکیده انگلیسی مقاله Background: Cardiac involvement in systemic sclerosis (SSc) is more prevalent than previously thought. In this study, the frequency and severity of cardiovascular involvement were assessed in SSc patients referred to Firouzgar Hospital. Methods: Fifty-eight patients with SSc, selected from the data bank of SSc patients, were reviewed for the frequency and severity of 8 organ involvements in this case series. The preliminary severity scale, published by international SSc study groups, was employed for the determination of the severity grade in the cardiovascular system. In the cardiac scoring scale, grade 0 represents normal heart (no cardiac involvement), grade 1 denotes mild involvement [ electrocardiography (ECG) conduction defect and a left ventricular ejection fraction (LVEF) of 45-49%)], grade 2 signifies moderate involvement (arrhythmia, LVEF = 40-44%), grade 3 indicates severe involvement (LVEF < 40%)], and grade 4 stands for end stage (congestive heart failure and arrhythmia requiring treatment). Results: In this study, 24 (41.4%) patients were in the diffuse cutaneous (dcSSc) subset. The female to male ratio was 10.5:1, and the mean duration from symptom onset to diagnosis was 7.35 years for the dcSSc subset and 8.41 years for the limited cutaneous (lcSSc) subset of disease, there being no significant difference. Cardiac involvement in this series was seen in 13 (22.4%) cases, and there was no significant difference in terms of frequency and severity between the two disease subgroups (p value = 0.96 and p value = 0.46 respectively). Conclusion: Our findings showed that the cardiac involvement in this series was infrequent and that there was no significant difference in the severity of cardiovascular involvement between the two subtypes of SSc in the late stage of the disease.
کلیدواژه‌های انگلیسی مقاله Scleroderma, systemic , Connective tissue diseases , Heart
نویسندگان مقاله هادی پورمقیم | hadi poormoghim
firouzgar hospital, iran university of medical sciences iums , tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

محمد علی پورکریم | mohamad ali poorkarim
firouzgar hospital, iran university of medical sciences iums , tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

مازیار مرادی لاکه | maziar moradi lakeh
department of community medicine, iran university of medical sciences iums , tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

بهناز یونس حشمتی | behnaz nozary heshmati
firouzgar hospital, iran university of medical sciences iums , tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

سیمین الماسی | simin almasi
firouzgar hospital, iran university of medical sciences iums , tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

مجتبی حکیم | mojtaba hakim
labafi-nejad hospital, shaheed beheshtee university of medical sciences, tehran, iran.
نشانی اینترنتی http://jthc.tums.ac.ir/index.php/jthc/article/view/156
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