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لیزر پزشکی، جلد ۲۲، شماره ۲، صفحات ۲۴-۴۱

عنوان فارسی سیستم‌های پلیمری بر پایه آلژینات: فناوری‌های نوین در دارورسانی، خواص آنتی باکتریال و پانسمان زخم
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عنوان انگلیسی Alginate-based Polymer Systems: New Technologies in Drug Delivery, Antibacterial Properties and Wound Dressings
چکیده انگلیسی مقاله Introduction: Alginate-based polymer systems, as one of the new technologies in the field of medicine and pharmacy, play a prominent role in improving the performance of drug delivery, antibacterial properties and wound dressing. Alginate dressings have been introduced as a cornerstone in advanced wound care due to their exceptional biocompatibility, moisture retention and hemostatic properties. Recent innovations in alginate-based wound dressings include multifunctional biomaterials engineered to accelerate healing, reduce the risk of infection and increase patient comfort. This study reviews the latest advances in the technology of extraction/purification methods, properties and different forms of advanced alginate-based polymer systems.
Methods: These advances include the development of bioactive composite formulations, antimicrobial agents such as silver, growth factors and stimuli-responsive components that enable targeted and controlled therapeutic delivery. New approaches such as nanofibrous methods, smart hydrogels and 3D bioprinted structures enhance the functional and mechanical properties of dressings and facilitate sustained drug release and wound monitoring through integrated sensors.
Results: Studies have shown that alginate-based polymer systems can be better candidates for some of the desired biomedical applications.
Conclusions: This studies showed that alginate-based polymer systems such as hydrogels, scaffolds and microspheres are suitable choices for wound healing purposes compared to other reported materials.
کلیدواژه‌های انگلیسی مقاله Alginate, Bioactive Agents, Wound Dressing, Controlled Drug Delivery, Advanced Polymer Systems

نویسندگان مقاله فاطمه حقدوست | Fatemeh Haghdoost
Department of Regenerative Medicine in Wound Healing, Medical Laser Research Centre, Yara Institute, ACECR, Tehran, Iran
جهاد دانشگاهی علوم پزشکی تهران

سروش شمس | Sorosh Shams
Department of Regenerative Medicine in Wound Healing, Medical Laser Research Centre, Yara Institute, ACECR, Tehran, Iran
جهاد دانشگاهی علوم پزشکی تهران

مسعود حبیبی | Masoud Habibi
Department of Regenerative Medicine in Wound Healing, Medical Laser Research Centre, Yara Institute, ACECR, Tehran, Iran
جهاد دانشگاهی علوم پزشکی تهران

محسن فاتح | Mohsen Fateh
Department of Life Style Medicine, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran
جهاد دانشگاهی علوم پزشکی تهران

مهرانگیز توتونچی | Mehrangiz Totonchi
Department of Medical Laser, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran
جهاد دانشگاهی علوم پزشکی تهران


نشانی اینترنتی http://icml.ir/browse.php?a_code=A-10-587-2&slc_lang=fa&sid=1
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