این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Otorhinolaryngology، جلد ۳۸، شماره ۱، صفحات ۶۱-۶۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Mantle Cell Lymphoma Mimicking Parotid Neoplasm: A Rare Case Report
چکیده انگلیسی مقاله Introduction:Mantle cell lymphoma (MCL) is a rare and aggressive B-cell non-Hodgkin lymphoma, commonly affecting lymph nodes, spleen, bone marrow, and gastrointestinal tract. Salivary gland involvement, especially in the parotid gland, is unusual and often mimics benign conditions, complicating diagnosis.Case Report:A 58-year-old male presented with a painless, progressively enlarging swelling in the right preauricular region without facial nerve involvement. Imaging revealed a mass within the parotid gland, leading to superficial parotidectomy. Histopathology confirmed mantle cell lymphoma. Immunohistochemical studies showed positivity for CD20, BCL2, CD5, and Cyclin D1; negativity for CD23, CD10, BCL6, and MUM1; and scattered CD3-positive T lymphocytes. The Ki-67 proliferation index was approximately 40%, indicating intermediate proliferative activity. Whole-body PET-CT revealed additional metabolically active lesions suggestive of systemic disease. The patient was started on bendamustine and rituximab chemotherapy.Conclusion:This case highlights that parotid swellings may conceal systemic lymphomas, and misleading cytology can delay diagnosis. Clinicians should consider MCL in atypical parotid lesions to ensure early systemic therapy.
کلیدواژه‌های انگلیسی مقاله Mantle Cell Lymphoma, Parotid gland, Immunohistochemistry (IHC)
نویسندگان مقاله | Tejaswi Gupta
Department of Otorhinolaryngology (ENT), UPUMS, Saifai, Etawah, 206130. India.


| Sanjeev Yadav
Department of Otorhinolaryngology (ENT), UPUMS, Saifai, Etawah, 206130. India.


| Ahmed Naseem
Department of Otorhinolaryngology (ENT), Dr KNS Memorial Institute of Medical Science. Barabanki, Pin code: 225001, India.


| Sanjeev Singh
Department of Pathology, UPUMS, Saifai, Etawah, 206130. India.


| Rashmi Rashmi
Department of Pathology, UPUMS, Saifai, Etawah, 206130. India.
نشانی اینترنتی https://ijorl.mums.ac.ir/article_27233.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Case Report
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات