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Journal of Arthropod-Borne Diseases، جلد ۱۹، شماره ۳، صفحات ۱۸۴۷-۱۸۴۷
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عنوان انگلیسی The Association between Demodex Infestation and Hair Loss Severity in a Referred Patient Population
چکیده انگلیسی مقاله Background: Hair follicle mites of the genus Demodex (Prostigmata: Demodicidae) are the most common external obligate parasites in humans, which reside in the eyelids, sebaceous glands, and ear canal, and can cause clinical dis­ease. The purpose of this study was to investigate the possible role of Demodex parasites in causing discomfort in pa­tients referred to Tehran laboratories due to hair loss. Methods: This cross-sectional study was conducted on 520 patients referred to a laboratory in Tehran, Iran, presenting with hair loss. Sampling was performed from the scalp and face, and samples were examined for Demodex mites using light microscopy. Results: The results showed that among the 520 patients referred to the laboratory, 66.15% were infected with Demo­dex. Out of 344 positive cases, 83.43% were women and 16.57% were men. Among the affected patients aged between 7 and 70 years, most patients (59.01%) were in the age group of 25.4 to 39.2 years. A high prevalence of Demodex in­festation (66.15%) was found among patients with hair loss.  Conclusion: Our findings establish a highly significant, direct correlation between the severity of hair loss and the den­sity of Demodex mite infestation (p< 0.001). We propose that high Demodex mite density is a significant contributory factor in the etiology of severe hair loss.
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نویسندگان مقاله | Abozar Nasiri-Jahrodi
Department of Pathobiology and Medical Laboratory Sciences, North Khorasan University of Medical Sciences, Bojnurd, Iran


| Hassan Bakhshi
Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran


| Rezvan Rajabzadeh
Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran


| Kamy Hosseinian-Khosroshahy
Department of Clinical Pathology, Dr. Khosroshahi&#x2019;s Pathobiology Laboratory, Tehran, Iran


| Hassan Reza Rokni
Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran


| Mehdi Barati
Department of Pathobiology and Medical Laboratory Sciences, North Khorasan University of Medical Sciences, Bojnurd, Iran


| Mitra Salehi
Vector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
نشانی اینترنتی https://jad.tums.ac.ir/index.php/jad/article/view/1847
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