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Journal of Arthropod-Borne Diseases، جلد ۱۹، شماره ۳، صفحات ۱۸۶۶-۱۸۶۶
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عنوان انگلیسی Assessment of the Impact of Diflubenzuron on the Inhibition of Adult Emergence in Aedes aegypti (Diptera: Culicidae) from Hormozgan Province, Iran, 2025
چکیده انگلیسی مقاله Background: The presence of Aedes aegypti in Iran and the risk of transmitting viral diseases, such as dengue and Zika, underscore the importance of evaluating effective vector control methods. Methods: This study investigated the effectiveness of diflubenzuron, an insect growth regulator that inhibits chitin syn­thesis, in preventing adult emergence of Ae. aegypti larvae from Hormozgan. The concentrations of 0.03, 0.06, 0.12 and 0.24 mg/L of 25% wettable powder formulations of diflubenzuron were used, according to WHO protocols. Results: Diflubenzuron was highly effective at 0.24 mg/L, achieving 98% emergence inhibition (EI50=0.053 mg/L, EI90=0.146 mg/L). At lower concentrations, e.g., 0.12 mg/L, emergence inhibition decreased to 83%, indicating a clear concentration-dependent reduction in efficacy. Larvae exposed to sublethal doses displayed abnormal movements and reduced responses to stimuli. Conclusion: This experiment supports diflubenzuron’s potential as an effective larvicide for vector control programs in Iran. However, field trials and resistance monitoring are recommended before widespread implementation.
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نویسندگان مقاله | Saeedeh Ebrahimi
Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Hassan Vatandoost
Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Mohammad Ali Oshaghi
Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Kourosh Azizi
Department of Medical Entomology and Vector Control, Research Center for Health Sciences, Institute of Health, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran


| Mahnaz Khanavi
Department of Pharmacognosy, School of Pharmacy and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran


| Seyed Hassan Moosa-Kazemi
Department of Vector Biology and Control of Diseases, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی https://jad.tums.ac.ir/index.php/jad/article/view/1866
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