| چکیده انگلیسی مقاله |
Background: Alpinia officinarum Hance (A. officinarum) roots are used as a treatment for various illnesses, including colds, stomachaches, inflammation, and discomfort. Objective: This work aimed to evaluate the anatomy, chemical compounds, antioxidant, antimicrobial, and anti-inflammatory activities of A. officinarum roots essential oil (EO). Methods: First, the plant's anatomy was studied by the alum-green iodine staining 0method, followed by steam distillation to extract EOs. The determination of chemical compositions by Gas chromatography-mass spectroscopy (GC-MS). The antioxidant activities were conducted by free radical resistance by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ABTS (2,2-Azino-bis-3-ethylbenzothiazoline-6-sulphonic acid), and FRAP (Ferric Reducing Antioxidant Power). The paper plate method was used to determine antimicrobial activity. Finally, the anti-denaturation of the Bovine serum albumin assay was measured for the anti-inflammatory properties of EO. Results: Anatomical results show that the EO of A. officinarum is distributed in the form of secretory sacs. By GC-MS, twenty-eight components were identified; the main compounds are Eucalyptol (24.57 %), β-Bisabolene (9.72 %), and β-Sesquiphellandrene (5.95 %). The IC50 of FRAP, ABTS, and DPPH assays are 810.00 µg/mL, 1343.71 µg/mL, and 26953.21 µg/mL, respectively. In addition, the EO exhibited anti-inflammatory activity with an IC50 of 2.55 mg/mL, compared to the standard Diclofenac (1.03 mg/mL). Additionally, the antimicrobial activity test demonstrated that the EO exhibited antimicrobial activity against various bacterial strains, including Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, Bacillus cereus, and Listeria innocua. Conclusions: These findings demonstrate that EOs can be utilized in the production of anti-inflammatory compounds and ferric-reducing additives. |
| نویسندگان مقاله |
| Thi Bich Thuyen Nguyen
Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
| Men Tran Thanh
Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
| Lien Huong Huynh
Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
| Lưu Ngoc Hanh Cao
Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
|