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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۲۰، شماره ۱، صفحات ۱۱۰-۱۱۶
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عنوان انگلیسی When the Skin Speaks for the Bone Marrow: Sweet Syndrome and Pancytopenia as the Initial Manifestation of Occult AML
چکیده انگلیسی مقاله This case report describes the presentation for a 65-year-old patient with Sweet's syndrome (SS) presenting with systemic symptoms of general weakness, fever, and painful skin lesions on the right arm. He reported a history of weight loss with night sweats, while skin lesions manifested as erythematous plaques and painful papules. The diagnosis was confirmed by skin biopsy, which showed features of significant neutrophilic infiltrations on histopathology. Further investigations led to the diagnosis of AML associated with Sweet's syndrome. The study highlights the importance of prompt diagnosis of Sweet's syndrome as a paraneoplastic sign and using multi-disciplinary approach for diagnosis and management of patients with skin lesions and cytopenias.  
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نویسندگان مقاله | Sohrab Aghabeigi
Hematologic Malignancies Research Center, Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran


| Nooshin Ahmadvand
Shahid Dr. Beheshti Clinical Research Development Unit, Shahid Dr. Beheshti-Anzali Educational and Medical Hospital, Guilan University of Medical Sciences, Rasht, Iran


| Seyedeh Mohadese Mosavi Mirkalaie
Student Research Committee, School of Medicine, Anzali International Campus, Guilan University of Medical Sciences, Rasht, Iran


| Azadeh Sedighi Moghadam
Razi Pathobiology Lab, Rasht, Iran


| Arefeh Aref-Eshghi
Shahid Dr. Beheshti Clinical Research Development Unit, Shahid Dr. Beheshti-Anzali Educational and Medical Hospital, Guilan University of Medical Sciences, Rasht, Iran
نشانی اینترنتی https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/2600
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