این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۱۸، شماره ۱، صفحات ۳۲-۴۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Burden and resistance of Gram-negative pathogens in ICU-acquired infections in Vietnam: a cross-sectional study
چکیده انگلیسی مقاله Background and Objectives: This study aimed to describe the burden, pathogen distribution, antimicrobial resistance patterns, and selected clinical outcomes of intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections in Vietnam, with exploratory comparative analyses of outcomes. Materials and Methods: A retrospective descriptive study with comparative analyses was conducted among 102 adult patients with culture-confirmed ICU-acquired GNB infections at E Hospital, Hanoi. Demographic, clinical, microbiological, and outcome data were extracted from medical records. Antimicrobial susceptibility testing was performed according to Clinical and Laboratory Standards Institute guidelines. Comparisons between outcome groups were assessed using chi-square test, with effect sizes quantified using Cramer’s V. Results: Pneumonia was the predominant infection (70.5%), followed by urinary tract (15.2%) and bloodstream infections (10.6%). GNB accounted for 68.3% of all hospital-acquired infections (HAIs), with Acinetobacter baumannii (43.4%), Pseudomonas aeruginosa (24.8%), and Klebsiella pneumoniae (13.9%) being the most frequent pathogens. The predominant pathogens exhibited extensive resistance to β-lactams, cephalosporins, and carbapenems. Susceptibility was largely retained only to colistin, tigecycline, and amikacin. Mechanical ventilation was significantly associated with death or a severe clinical outcome (p = 0.03; Cramer’s V = 0.21). Conclusion: GNB dominate ICU-acquired infections in Vietnam and demonstrate alarming antimicrobial resistance, underscoring the urgent need for strengthened infection control and antimicrobial stewardship.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Do Phong
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Vu Vinh
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Dang Van
Department of Infection Control, E Hospital, Hanoi, Vietnam


| Tran Hieu
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Tran Huong
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Le Thuong
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Le Duc
Department of Intensive Care Unit, E Hospital, Hanoi, Vietnam


| Nguyen Huong
Medical Check-up Clinic, E Hospital, Hanoi, Vietnam
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/5861
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات