| چکیده انگلیسی مقاله |
Background and purpose: Kawasaki disease is the most common form of vasculitis in children, affecting medium- and small-sized vessels and often involving the coronary arteries. This study aimed to investigate the frequency of COVID-19 in children with Kawasaki disease.
Materials and methods: This descriptive cross-sectional study was conducted at Afzalipour Hospital in Kerman, Iran, between 2020 and 2021. All patients diagnosed with Kawasaki disease were included using a non-probability convenience sampling method. Patients were divided into two groups: COVID-19–positive and COVID-19–negative. The variables of interest were then compared between the two groups. Data were recorded in a standardised data collection form and subsequently analyzed. Descriptive and inferential statistical methods were applied using SPSS.
Results: A total of 201 children diagnosed with Kawasaki disease were included in the study. The mean age of the children was 32.82 ± 3.05 months. The mean C-reactive protein (CRP) level was 31.06 ± 3.10 mg/L, and the mean erythrocyte sedimentation rate (ESR) was 50.55 ± 3.37 mm/h. Boys constituted the majority of cases (53.7%); although the disease was more prevalent in boys, the difference was not statistically significant (P= 0.82). Overall, 21.9% of children with Kawasaki disease were polymerase chain reaction (PCR)-positive for COVID-19. More than 76% of the children (76.1%) had a strawberry tongue, 63.2% had conjunctivitis, and 46.3% presented with a maculopapular rash. The mean age of children with PCR-positive Kawasaki disease (35.10 ± 2.54 months) was significantly higher than that of children with PCR-negative Kawasaki disease (25.59 ± 3.03 months) (P = 0.01).
Conclusion: The findings of this study showed that 21.9% of children with Kawasaki disease during the COVID-19 pandemic had a positive PCR test and presented with clinical manifestations such as strawberry tongue, conjunctivitis, and maculopapular rash. However, the potential association between SARS-CoV-2 infection and Kawasaki disease warrants further investigation in paediatric populations.
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| نویسندگان مقاله |
مهدی شهریاری | Mahdi Shahriari
General Practitioner, Kerman University of Medical Sciences, Kerman, Iran
دکتری عمومی، دانشگاه علوم پزشکی کرمان، کرمان، ایران
محمدعلی جعفری | Mohammad Ali Jafari
PhD, Department of Veterinary Basic Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
دکتری دامپزشکی، گروه علوم پایه دامپزشکی، واحد علوم و تحقیقات، دانشگاه آزاد اسلامی، تهران، ایران
علی حسینی نسب | Ali Hosseininasab
Associate Professor, Department of Pediatrics, School of Medicine, Infectious and Tropical Research Center, Kerman University of Medical Sciences, Kerman, Iran
دانشیار بیماریهای عفونی کودکان، گروه اطفال، دانشکده پزشکی، مرکز تحقیقات بیماری های عفونی و گرمسیری، دانشگاه علوم پزشکی کرمان، کرمان، ایران
سعیده پرورش | Saeedeh Parvaresh
Assistant Professor, Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
استادیار بیماریهای کلیه (کودکان )، گروه اطفال، دانشکده پزشکی، دانشگاه علوم پزشکی کرمان، کرمان، ایران
مریم احمدی پور | Maryam Ahmadipour
Associate Professor, Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
دانشیار قلب کودکان، گروه اطفال، دانشکده پزشکی، دانشگاه علوم پزشکی کرمان، کرمان، ایران
رضا سینایی | Reza Sinaei
Assistant Professor, Department of Pediatrics, School of Medicine, Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
استادیار روماتولوژی کودکان، گروه اطفال، دانشکده پزشکی، دانشگاه علوم پزشکی کرمان، کرمان، ایران؛ مرکز تحقیقات غدد درون ریز و متابولیسم، پژوهشکده علوم فیزیولوژی بالینی و پایه دانشگاه علوم پزشکی کرمان، کرمان، ایران
اعظم دهقانی | Azam Dehghani
MSc in Biostatistics, Gastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
کارشناس ارشد آمار زیستی، مرکز تحقیقات گوارش و کبد، پژوهشکده فیزیولوژی بالینی و پایه، دانشگاه علوم پزشکی کرمان، کرمان، ایران
فاطمه کرمی رباطی | Fatemeh Karami Robati
PhD Student in Medical Library and Information Sciences, Clinical Research Development Unit, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran
دانشجوی دکتری کتابداری و اطلاع رسانی پزشکی، واحد توسعه تحقیقات بالینی، بیمارستان افضلی پور، دانشگاه علوم پزشکی کرمان، کرمان، ایران
مائده جعفری | Maedeh Jafari
Assistant Professor, Department of Pediatrics, School of Medicine, Research Center for Hydatid Disease in Iran, Afzalipour Hospital, Kerman University of medical Sciences, Kerman, Iran
استادیار بیماریهای عفونی کودکان، گروه اطفال، دانشکده پزشکی، بیمارستان افضلی پور، مرکز تحقیقات بیماری هیداتید، دانشگاه علوم پزشکی کرمان، کرمان، ایران
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