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Iranian Journal of Medical Physics، جلد ۲۲، شماره ۶، صفحات ۴۳۰-۴۳۸
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عنوان انگلیسی Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT
چکیده انگلیسی مقاله Introduction: This study evaluated the potential of the Varian Halcyon LINAC and its associated Portal Dosimetry (PD) software, using in vivo megavoltage portal images, as a tool for in vivo portal dosimetry constancy (IVDc) in head and neck cancer (HNC) patients receiving volumetric modulated arc therapy (VMAT).Material and Methods: A retrospective study included 100 HNC patients (mean age 58.4 ± 9.2 years; 72 males, 28 females) treated with three arc VMAT plans on the Halcyon LINAC. A prescription dose of 7000 cGy was delivered over 35 fractions to high risk volumes and 6300 cGy to intermediate risk volumes. Portal images from all fractions (3500) and arcs (10,500) were compared to first fraction baselines via gamma analysis with a 3%/2 mm criterion and 95% passing threshold. Phantom tests evaluated sensitivity to thickness changes.Results: Gamma passing rates exhibited a steady decline over the treatment course (R²=0.9724), with an average 93.9 ± 3.6% passing rate, dropping below 90% after 25 fractions. Failures correlated with thickness variations exceeding 1 cm, which were detected with high accuracy during phantom tests. Pretreatment patient-specific QA yielded 100% pass rates.Conclusion: This study demonstrates the potential of the Halcyon LINAC's integrated PD system and Varian PD software for IVDc in HNC patients treated with VMAT. The results confirm the feasibility of using in vivo MV portal images acquired on the Halcyon LINAC to assess dose consistency throughout treatment.
کلیدواژه‌های انگلیسی مقاله Head and Neck Neoplasms Radiotherapy Intensity, Modulated Radiotherapy Planning Computer, Assisted
نویسندگان مقاله | Venugopal Sundaram
Division of Physical Sciences, Karunya Institute of Technology and Sciences, Coimbatore, Tamilnadu, India.


| David Khnna
Division of Physical Sciences, Karunya Institute of Technology and Sciences, Karunya Nagar, Coimbatore, India- 641 114


| Mohandass P
Department of Radiation Oncology, Fortis Hospital, Mohali, Punjab, India.


| Prabhu R
Department of Radiation Oncology, Yashoda Super Specialty Hospital and Cancer Institute, Sanjay nagar, Ghaziabad, U.P. India.


| Sathyaraj Palanivel
Department of Radiation Oncology, Kidwai memorial institute of oncology center, Bengaluru, India.


| Rekha Arya
Department of Radiation Oncology, Yashoda Super Specialty Hospital and Cancer Institute, Sanjay nagar, Ghaziabad, U.P. India.


| Nilotpal Chakravarty
Department of Radiation Oncology, Yashoda Super Specialty Hospital and Cancer Institute, Sanjay nagar, Ghaziabad, U.P. India.


| Antovaz S
Division of Physical Sciences, Karunya Institute of Technology and Sciences, Coimbatore, Tamilnadu, India.


| Palanivel D
Division of Physical Sciences, Karunya Institute of Technology and Sciences, Coimbatore, Tamilnadu, India.
نشانی اینترنتی https://ijmp.mums.ac.ir/article_27451.html
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