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Iranian Journal of Parasitology، جلد ۱۱، شماره ۱، صفحات ۱۱۶-۱۲۰
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عنوان انگلیسی Cerebral Malaria Treated with Artemisinin in the Intensive Care Unit: A Case Report
چکیده انگلیسی مقاله Malaria is a parasitic disease that is starting to be encountered in intensive care units (ICU) worldwide, owing to increasing globalisation. Severe malaria caused by Plasmodium falciparum , is characterised by cerebral malaria, acute renal failure, hypoglycaemia, severe anaemia, splenomegaly and alveolar oedema. We present the case of a 25-yr old male patient who presented to the Emergency Department of Uludag University in Bursa, Turkey in the winter of 2014 with complaints of fe­ver for three days. His medical history revealed a 14-month stay in Tanzania. Staining of blood smears revealed characteristic gametocytes in accordance with P. falciparum infection. The day after admission, he had an epileptic seizure after which his Glasgow Coma Scale was 6, so he was intubated and transferred to the ICU. A computerized tomography scan revealed findings of cerebral oedema. Intravenous mannitol was administered for 6 days. Intravenous artemisinin was continued for 10 days. Due to refractory fevers, anti-malarial treatment was switched to quinine and doxycycline on the 14th day and on the 16th day the fe­vers ceased. This case emphasizes that cerebral malaria should be suspected in cases of seizures accompanying malaria, and treatment should be initiated in the ICU. Furthermore, resistance of P. falciparum to artemisinin should be in mind when a response to therapy is lacking.
کلیدواژه‌های انگلیسی مقاله Artemisinin, Cerebral malaria, Intensive care unit
نویسندگان مقاله elif ayşe çizmeci | elif ayşe çizmeci


nermin kelebek girgin | nermin kelebek girgin


ilkay ceylan | ilkay ceylan


tekin tuncel | tekin tuncel


اکتای alver | oktay alver


emin halis akalin | emin halis akalin


نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/819
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Case Report(s)
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