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Iranian Journal of Parasitology، جلد ۱۰، شماره ۲، صفحات ۲۷۳-۲۷۹
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Histological Changes of the Ovary in Pregnant Mice Vaginally Exposed to Toxoplasma gondii.
چکیده انگلیسی مقاله Background: Congenital toxoplasmosis is one cause of abortion. Infection can disrupt ovarian cycles and because toxoplasmosis is an infectious disease may have a similar effect on the ovaries. The purpose of this study was to investigate the pathological changes in the ovaries due to toxoplasmosis. Methods: Tachyzoites of Toxoplasma gondii were harvested from peritoneal fluid of mice, experimentally infected. Two females and one male mouse were housed per cage for mating in the overnight. The pregnant mice were divided into experi-mental and control groups. Experimental group were infected by parasite but the control group received the normal saline. The experimental and control mice were euthanized. Ovaries and uterine horns of animals were removed and prepared for light microscopy. Results: Ovaries of infected pregnant mice presented gross morphological differ-ences compared to the control groups. In ovaries of experimental groups, changes of corpus luteum were observed. The comparison of experimental and control groups revealed that the number of primary follicles, secondary follicle, atretic pri-mary follicles and atretic secondary follicles had significant differences ( P ≤0.001). Conclusion: Toxoplasma gondii alters ovarian follicular growth and development in mice. In addition, it alters number of different phases of follicles and corpus lu-teum in ovaries of mice.
کلیدواژه‌های انگلیسی مقاله Corpus luteum,Histology,Ovarian follicles,Toxoplasma gondii
نویسندگان مقاله زهرا اسلامی راد | zahra eslamirad
dept. of parasitology, school of medicine, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

پروین دخت بیات | parvin dokht bayat
dept. of anatomy, school of medicine, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

سعید بابایی | saeid babaei
dept. of anatomy, school of medicine, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/323
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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