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Iranian Journal of Parasitology، جلد ۶، شماره ۱، صفحات ۱-۱۱
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عنوان انگلیسی Epidemiological Aspects of Visceral Leishmaniasis in Baft District, Kerman Province, Southeast of Iran
چکیده انگلیسی مقاله Background : Visceral leishmaniasis (kala-azar) is an endemic disease in some areas of Iran. A cross- sectional study was conducted for sero-epidemiological survey of visceral leishmaniasis (VL) in Baft district from Kerman Province, southeast of Iran. Methods: Blood samples were collected from children up to 12 years old and 10% of adult population from Baft villages with a multi-stage randomized cluster sampling. In addition, blood samples were collected from 30 domestic dogs from the same areas. All the collected blood sam­ples were tested by direct agglutination test (DAT) for the detection of anti- Leishmania antibod­ies in both human and dog using the cut-off value of ≥1:3200 and ≥ 1:320, respectively. Parasitologi­cal, molecular, and pathological were performed on infected dogs. Chi-square and Fisher exact tests were used to compare sero-prevalence values. R esults: From 1476 collected human serum samples, 23 (1.55%) showed anti- Leishmania antibod­ies at titers of 1:800 and 1:1600 whereas 14 (0.95%) showed anti- Leishmania infantum antibodies at titers of ≤ 1:3200. No statistically significant difference was found between male (1.18 %) and female (0.69%) sero-prevalence ( P= 0.330). Children of 5-8 years showed the high­est sero-prevalence rate (3.22%). Seven out of 30 domestic dogs (23%) showed anti- Leishmania antibodies at titers ≤ 1:320. Leishmania infantum was identified in five infected dogs by nested - PCR assay. Conclusion: It seems that visceral leishmaniasis is being endemic in southern villages of Baft district, southeast of Iran.
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نویسندگان مقاله h محمودوند | h mahmoudvand
department of medical parasitology and mycology, school of public health, ehran university of medical sciences, tehran, iran


m محبعلی | m mohebali
department of medical parasitology and mycology, school of public health, ehran university of medical sciences, tehran, iran


i شریفی | i sharifi
dermatology and leishmaniasisn research centre, school of medicine, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

h کشاورز | h keshavarz
department of medical parasitology and mycology, school of public health, ehran university of medical sciences, tehran, iran


h حجاران | h hajjaran
department of medical parasitology and mycology, school of public health, ehran university of medical sciences, tehran, iran


b آخوندی | b akhoundi
department of medical parasitology and mycology, school of public health, ehran university of medical sciences, tehran, iran


جهان بخش | s jahanbakhsh
dermatology and leishmaniasisn research centre, school of medicine, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

m زارعان | m zarean
dermatology and leishmaniasisn research centre, school of medicine, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

علی | a javadi
department of pathology, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/159
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