این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Medical Journal of Islamic Republic of Iran، جلد ۲۸، شماره ۱، صفحات ۳۵۷-۳۶۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Causality relationships between coagulation factors in type 2 diabetes mellitus: path analysis approach
چکیده انگلیسی مقاله  Background: Type 2 diabetic mellitus patients are amongst the most susceptible groups to vascular abnormalities, which predominantly lead to myocardial disease. The hypercoagulable state has been widely studied by researchers as being the major suspicious mechanism facilitating the consecutive chain of molecular events leading to these complications. However, there is no consensus on the definition of the hypercoagulable state with respect to coagulation quantities, their interrelations and basic factor(s) initiating this pathogenic event, by which the prognosis of myocardial complications could be determined. Methods: Path analysis was used to study the interactions between coagulation factors as well as other factors beyond coagulation factors in relation with pathogenic events in both diabetics and healthy subjects. In the present work, coagulation factors of 40 healthy and 40 type 2 diabetics were determined experimentally. The data were then analyzed using SPSS and AMOS software. Multivariate regression analysis was done to draw path diagrams. Results: Our results show that FII, as the main cause for hypercoagulable state, is directly induced by FX and FVIII in normal individuals and by FX, FXI, FV and VWF cofactors in diabetic patients. Conclusion: In general, our findings showed complicated relationship between coagulation factors and their effects either separately or combined.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمدرضا دایر | mohammad reza dayer
department of biology, faculty of science, shahid chamran university, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

میثم مرد سلطانی | maysam mard soltani
medical education development center, dezful university of medical sciences, dezful, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی دزفول (Dezful university of medical sciences)

محمدسعید دایر | mohammad saaid dayer
faculty of medical sciences, tarbiat modares university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

سید محمد رضا علوی | sayed mohammad reza alavi
department of statistics, faculty of mathematics and computer sciences, shahid chamran university, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه شهید چمران (Shahid chamran university)

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-689&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده 1
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات