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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۷، شماره ۴، صفحات ۱۰-۱۴
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عنوان انگلیسی Growth Parameters and Vitamin D status in Children with Thalassemia Major in Upper Egypt.
چکیده انگلیسی مقاله Aim: the aim of this study is to assess the growth parameters, vitamin D, calcium, and phosphorous status in children with thalassemia major receiving packed red cells transfusion with chelation therapy. Patients and Methods: In a case control study, 100 patients with beta thalassemia major (aged from 4 to 15 years) were compared with 100 sex- and age-matched children serves as a control group. Anthropometric measurement, Serum level of calcium, phosphorus and vitamin D (25 hydroxycholecalciferol) were estimated for all patients & controls. Results: 49% of our patients had short stature. 47% were underweight. BMI of 43 (43%) patients were low. The mean total serum calcium (6.6±1.2 mg/dl) and 25-hydroxycholecalciferol (25-OH Vit D) (10.4±4.6 mcg/dl) levels were significantly lower in our patients than in controls (10.2±1.06 mg/dl and 40.2±12.3 mcg/dl, respectively); each P< 0.001. Conclusion: Children with beta thalassemia major have delayed growth and metabolic abnormalities that signify the importance of therapeutic interventions. The presence of these abnormalities may be due to iron overload and poor nutritional support.
کلیدواژه‌های انگلیسی مقاله Calcium,Growth,Thalassemia major,Vitamin D
نویسندگان مقاله فهیم m فهیم | fahim m fahim
department of pediatrics, assiut university, assiut 71516, egypt.


خالد سعد | khaled saad
department of pediatrics, assiut university, assiut 71516, egypt.


ایمان a عسکر | eman a askar
department of pediatrics, assiut university, assiut 71516, egypt.


ایمان نصر الدین | eman nasr eldin
department of clinical pathology, assiut university, assiut 71516, egypt.


احمد f thabet | ahmed f thabet
department of internal medicine, assiut university, assiut 71516, egypt.
نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/442
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