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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۷، شماره ۴، صفحات ۳۴-۳۹
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عنوان انگلیسی Anemia and thrombocytopenia in acute and chronic renal failure.
چکیده انگلیسی مقاله Background: Acute renal failure describes as a syndrome by rapid decline in the ability of the kidney to eliminate waste products, regulate acid–base balance, and manage water homeostasis. When this impairment is prolonged and entered chronic phase, erythropoietin secretion by this organ is decreasing and toxic metabolic accumulates and causes hematological changes include decrease of HCT, MCV and RBC and platelet counts. This study evaluates present of anemia and thrombocytopenia in patients with acute and chronic renal failure. Materials and Methods: This study conducted on 132 patients with renal impairment and also 179 healthy individuals as two separated control groups. Initially patients with renal problem were tested and after confirmation of impairment, patients were divided in two groups, acute with less than 3 months and chronic with more than 3 months renal failure, based on duration of the disease. Then complete blood count performed for each patient and finally obtained data were analyzed by SPSS software. Results: Comparison between 96 patients with acute and 36 patients with chronic renal failure revealed that severity of anemia (HCT, Hb and MCV) between these two groups were statistically high in comparison with control groups (P>0.05) but thrombocytopenia in patients with chronic renal failure was statistically different from control and the acute ones (P< 0.001). Conclusion: It was recommended that in patients with chronic renal failure, to prevent the risk of bleeding, platelet count should be checked periodically.
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نویسندگان مقاله اکبر درگلاله | akbar dorgalaleh
hematology department, allied medical school, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد محمودی | mohammad mahmudi
pars pathobiology laboratory, minoodasht, golestan, iran.


شادی طبیبیان | shadi tabibian
hematology department, allied medical school, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

زهرا کاشانی خطیب | zahra kashani khatib
hematology department, allied medical school, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

غلام حسین تمدن | gholam hossein tamaddon
department of laboratory sciences, faculty of paramedical sciences, shiraz university of medical sciences and health servies, shiraz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

اسماعیل صانعی مقدم | esmaeil sanei moghaddam
blood transfusion research center, high institute for research and education in transfusion medicine and zahedan regional educational blood transfusion center, iran.

سازمان اصلی تایید شده: سازمان انتقال خون ایران (Blood transfusion research center)

طارق بامدی | taregh bamedi
parasitology department, zahedan university of medical sciences, zahedan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

شعبان علیزاده | shaban alizadeh
hematology department, allied medical school, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

اسحاق مرادی | eshagh moradi
medical education department, medical faculty, university of medical sciences, tehran, iran.
نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/438
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