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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۵، شماره ۴، صفحات ۱۴-۱۷
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عنوان انگلیسی Serologic Prevalence of Human T-Lymphotropic Virus (HTLV) among major Thalassemic Patients in Kermanshah 2010
چکیده انگلیسی مقاله Introduction: Transfusion-transmitted infections (TTI) continue to be a major challenge for Blood transfusion organizations in the world and multi- transfused patients (MTPs) are at higher risk of infection. HTLV-1 is a retrovirus that easily transmitted via blood cell products. The aim of this study is determine the seroprevalence of HTLV-1 in major thalassemic patients from Kermanshah Province, western of Iran. Material and methods: A total of 116 serum samples from all major thalassemic patients that exist in Kermanshah providence and 1000 serum samples from healthy individuals as control group were tested for HTLV specific antibody by ELISA method. All of the ELISA positive samples were confirmed by Western Blotting analysis. Results: From major thalassemic patients, 4 subjects (3.4%) had HTLV-I infection. Also, among 1000 control individuals, 5 subjects (0.5%) had HTLV-I infection. There wasn’t any HTLV-II in major thalassemic patients or control individuals. Conclusion: our results showed this infection exist in our region. These results indicated that screening procedure were not doing carefully. More studies are needed to clarify the reason of this unsuccessfully screening of this virus from donated blood.
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نویسندگان مقاله کیقباد قدیری | keighobad ghadiri
department of pediatrics, school of medicine, kermanshah university of medical sciences, kermanshah, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

امیرحسین هاشمیان | amirhossein hashemian
department of biostatistics and epidemiology, faculty of public health, kermanshah university of medcal sciences, kermanshah, iran


منصور رضایی | mansour rezaei
department of biostatistics and epidemiology, faculty of public health, kermanshah university of medcal sciences, kermanshah, iran


مهرداد پاینده | mehrdad payandeh
medical biology research center, kermanshah university of medical sciences, kermanshah, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

محمد عرفان زارع | mohammad erfan zare
medical biology research center, kermanshah university of medical sciences, kermanshah, iran; studen

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/291
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