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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۴، شماره ۳، صفحات ۶-۹
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چکیده فارسی مقاله
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عنوان انگلیسی The Association Between Hypothyroidism and Anemia: a Clinical Study
چکیده انگلیسی مقاله Introduction: Hypothyroidism is diagnosed by elevated thyroid stimulating hormone (TSH) and normal or decreased serum levels of T4 or T3, and is associated with a wide range of m etabolic abnormalities, including anemia. This clinical study aimed to assess the improvement of anemia in patients with primary hypothyroidism following administration of levothyroxine in Iranian population. Materials & Methods: The effect of levothyroxine in 70 patients with hypothyroidism was examined and the improvement of anemia in patients who had a poor or good response to levothyroxine was assessed during a 3 month follow-up. Results: Three months after treatment, the levels of TSH in 64 patients with hypothyroidism (91.4%) significantly decreased to a normal limit (TSH< 2.5 IU/ml). Forty three out of 70 patients (61.4%) had a concurrent anemia. A significant difference was found in the levels of hematologic parameters between those who had a good response (TSH< 2.5 IU/ml) and those with poor responses to the treatment (TSH ≤ 2.5 IU/ml) (p< 0.05). Conclusions: Current study showed a high rate of association between anemia and hypothyroidism in Iranian population. Improvement in hypothyroidism and its associated anemia was observed in majority of patients (more than 90%), indicating a dual benefit for hypothyroidism treatment. Less than 10% of patients poorly responded to levothyroxine, with no clear reasons.
کلیدواژه‌های انگلیسی مقاله Anemia,Hypothyroidism,Iran,Levothyroxine
نویسندگان مقاله میترا کاظمی جهرمی | mitra kazemi jahromi
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran,iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علی شهریاری احمدی | ali shahriari ahmadi
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید حسین صمدانی فرد | seyed hosein samedanifard
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ثریا دوست محمدیان | soraya doostmohamadian
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

عصمت عبداله پور | esmat abdolahpoor
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید فرشاد علامه | seyed farshad allameh
hematology-oncology department, rasul akram hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/249
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