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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۲، شماره ۱، صفحات ۲۳-۲۵
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عنوان انگلیسی Study of D/G Hemoglobin incidence in a sample population (single institution)
چکیده انگلیسی مقاله Background: The hemoglobin disorders constitute the most prevalent group of monogenic disease A findings consis‌tent with this is a hemoglobin/G variant indicating that the patient has HbD/G trait. Hb D/G traits are clinically benign. In this study, the epidemiology of HbD/G was reviewed in a single institution in Iran. Methods and Materials: We conducted the epidemiological study at Aliasghar children's hospital and all patients with HbD/G were entered to this study. The hematological values, hemoglobin electrophoresis, peripheral blood smear and clinical findings were collected in the data special form. Results: Among 11825 hemoglobin analysis performed, we detected 101 cases of hemoglobin D/G. There were 55.4% male and 44.6% female, median age 9±13.36 yrs. Homozygous of D/G was found in seven pa‌tients with splenomegaly, jaundice, mild anemia and Reticulocytosis. Heterozygote patients were as‌ymptomatic. There wasn't any correlation between HbD/G with serum ferritin, MCV, Hb and sex. Conclusion: In Iran HbD/G is relatively benign condition with mild anemia, Poikylocytosis and minimal hemolysis.
کلیدواژه‌های انگلیسی مقاله Hemoglobin D/G,Hemoglobinopathis,Iran
نویسندگان مقاله kh ارجمندی | kh arjmandi
assistant professor of pediatric hematology and oncology, iran university of medical sciences, ali asghar children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

m فرانوش | m faranoush
assistant professor of hematology and oncology, semnan university of medical sciences, amir al momenin hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی سمنان (Semnan university of medical sciences)

gh باهوش | gh bahoush
assistant professor of pediatric hematology and oncology, iran university of medical sciences, ali asghar children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

p وثوق | p vossough
professor of pediatric hematology and oncology, iran university of medical sciences, ali asghar children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

aa هدایتی اصل | aa hedayatiasl
fellowship of pediatric hematology and oncology, iran university of medical sciences, ali asghar children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

sh انصاری | sh ansari
assistant professor of pediatric hematology and oncology, iran university of medical sciences, ali asghar children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

e شاهقلی | e shahgholi
assistant professor of pediatric hematology and oncology, tehran university of medical sciences, bahrami children’s hospital

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/178
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