این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Parasitology، جلد ۱۲، شماره ۳، صفحات ۳۷۴-۳۸۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Prevalence and Molecular Aspects of Human Hookworms in Guilan Province, Northern Iran
چکیده انگلیسی مقاله Background: Hookworm infection is one of the important Neglected Tropical Diseases (NTD) in the world. It was previously more prevalent in the northern and southern parts of Iran with a prevalence rate higher than 40% in some endemic regions; nevertheless, the infection rate has decreased to less than 1%. This study aimed to determine prevalence and molecular aspects of hookworm infections in rural inhabitants of Fouman County, Guilan Province, northern Iran Methods: This cross-sectional study was performed in 31 villages of Fouman district in Guilan Province, northern Iran during 2015-2016. Stool samples were collected from 1500 rural inhabitants and examined by formalin ethyl-acetate concentration as well as agar plate culture techniques. After treatment with albendazole, adult hookworms were isolated. FollowingDNA extraction,PCR amplification of ITS2-rDNA region was performed and the product was sequenced, followed by genetic variation analysis. Results: Of 1500 samples, one case was morphologically diagnosed as N. americanus . In addition, molecular characterization verified the presence of N. americanus, showing more than 95% similarity with sequences of N. americanus present in GenBank. The patient showed no clinical symptoms and a mild hypereosinophilia was the only laboratory finding observed. Conclusion: A reduced prevalence of human hookworms was demonstrated within Guilan Province located in north of Iran. The N. americanus originated from Guilan had a high homology with the isolates found in Japan, Laos, Malaysia, and Australia.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله میثم شریف دینی | meysam sharifdini
dept. of parasitology and mycology, school of medicine, qazvin university of medical sciences, qazvin, iran cellular and molecular research center, qazvin university of medical sciences, qazvin, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی قزوین (Qazvin university of medical sciences)

لاله قنبرزاده | laleh ghanbarzadeh
guilan province health center, guilan university of medical sciences, rasht, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (Guilan university of medical sciences)

نصرالله کوهستانی ماکلوانی | nasrolla kouhestani maklavani
foodborne and waterborne diseases research center, research institute for gastroenterology and liver diseases, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

حامد میرجلالی | hamed mirjalali
dept. of parasitology and mycology, school of medicine, qazvin university of medical sciences, qazvin, iran cellular and molecular research center, qazvin university of medical sciences, qazvin, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی قزوین (Qazvin university of medical sciences)

مهرزاد سرایی | mehrzad saraei


نشانی اینترنتی http://ijpa.tums.ac.ir/index.php/ijpa/article/view/1768
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/69/article-69-429502.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article(s)
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات