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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۱، شماره ۴، صفحات ۲۶۸-۲۷۲
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عنوان انگلیسی Complications of Transfusion-Dependent β-Thalassemia Patients in Sistan and Baluchistan, South-East of Iran
چکیده انگلیسی مقاله Background: Thalassemia syndromes are among prevalent hereditary disorders imposing high expenses on health-care system worldwide and in Iran. Organ failure represents a life-threatening challenge in transfusion- dependent β-thalassemia (TDT) patients. The purpose of the present study was to determine the frequency of organ dysfunctions among TDT patients in Sistan and Baluchistan province in South-East of Iran. Materilas and Methods: Laboratory and clinical data were extracted from medical records as well as by interviews. Standard criteria were applied to recognize cardiac, gonadal, endocrine and renal dysfunctions. The collected data were analyzed using the SPSS statistics software (Ver.19). Results: A total of 613 TDT patients (54.3% males and 45.7% females) were included in this study. The mean age of patients was 13.3 ± 7.7 years old. Cardiac events comprised the most encountered complications (76.4%), following by hypogonadism (46.8%), parathyroid dysfunction (22%), thyroid abnormalities (8.3%), diabetes (7.8%) and renal disease (1.8%). Hypogonadism comprised the most identified complication in patient < 15 years old, while the cardiac complications were the most frequent sequela in patients >15 years old (P< 0.01). Conclusion: As cardiac events are significantly more common among TDT patients, close monitoring of the heart function is recommended for identifying patients with cardiac problems.
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نویسندگان مقاله مریم یعقوبی | maryam yaghobi
1.genetics of non-communicable disease research centre, zums, zahedan, iran 2.cardiovascular diseases research center, birjand university of medical sciences, birjand, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بیرجند (Birjand university of medical sciences)

ابراهیم میری مقدم | ebrahim miri moghaddam
genetics of non-communicable disease research centre, zums, zahedan, iran


مجید نادری | majid naderi
clinical research development unit, amir-al-momenin hospital, zabol university of medical sciences, zabol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زابل (Zabol university of medical sciences)

علی بزی | ali bazi
department of mental health amp;amp; psychiatric nursing, pregnancy health research centre, zums, zahedan, iran


علی نویدیان | ali navidian
students scientific research center, faculty of nursing amp;amp; midwifery, zums, iran hospital, iranshhar, iran


آسیه کلکلی | asiyeh kalkali


نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/681
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/78/article-78-429907.pdf
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زبان مقاله منتشر شده en
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