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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۱۱، شماره ۳، صفحات ۲۵۱-۲۶۲
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چکیده فارسی مقاله
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عنوان انگلیسی Colorectal Cancer Screening: A Comprehensive Review to Recent Non-invasive Methods
چکیده انگلیسی مقاله Colorectal cancer (CRC) is one of the most common cancers worldwide and considered to be one of the hassle in medical communities. CRC develops from precancerous polyps in the colon or rectum and is preventable and curable by an early diagnosis and with the removal of premalignant polyps. In recent years, scientists have looked for inexpensive and safe ways to detect CRC in its earliest stages. Strong evidence shows that screening for CRC is a crucial way to reduce the incidence and mortality of this devastating disease. The main purpose for screening is to detect cancer or pre-cancer signs in all asymptomatic patients. In this review, we holistically introduce major pathways involved in the initiation and progression of colorectal tumorgenesis, which mainly includes chromosome instability (CIN), microsatellite instability (MSI), the CpG island methylator phenotype (CIMP), and we then will discuss different screening tests and especially the latest non-invasive fecal screening test kits for the detection of CRC.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله لیلا حمزه زاده | leila hamzehzadeh
department of medical genetics, faculty of medicine, mashhad university of medical sciences, mashhad, iran hematology, oncology and stem cell transplantation research center, shariati hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

میثم یوسفی | meysam yousefi
hematology, oncology and stem cell transplantation research center, shariati hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید حمیداله غفاری | seyed hamidollah ghaffari


نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/610
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/78/article-78-430389.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article(s)
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