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Medical Journal of Islamic Republic of Iran، جلد ۲۸، شماره ۱، صفحات ۳۷-۴۴
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عنوان انگلیسی Effect of aerobic exercise and fish oil supplements on plasma levels of inflammatory indexes in mice
چکیده انگلیسی مقاله  Background: Exercise has positive and negative effects on immune system. Herein, we would like to investigate the effects of incremental aerobic training and fish oil supplementation on the plasma levels of CRP, CPK and IL-17 in trained mice. One of the major roles of immune system is to produce soluble or cellular components that provide the immunity against inflammatory agent. The purpose of this study is to investigate distinct and combine effects of incremental aerobic training and fish oil supplement on plasma levels of IL-17, CPK and CRP in trained male mice. Methods: Totally, 54 healthy male mice (2 months old, weight= 34±1 grams) were selected. At first 10 mice were killed to determine base line values, the rest of them were randomly divided into four groups, control group (C, n=11), supplement group (S, n=11), training group (T, n=11) and supplement-training group (ST, n=11).The supplement and supplement-training groups were fed with 0.2cc/day fish oil for 8 weeks. Training and supplement-training groups underwent exercise for 5 sessions per week for a period of 8 weeks on animal treadmill. SPSS 16.0 software and multivariate analysis of variance were used for statistical analysis of data. Results: Exercise and fish oil supplement lead to a decrease in CRP levels and subsequently causing a reduction in plasma levels of IL-17 and CK in mice (p< 0.05). Conclusion: Combination of exercise and fish oil can reduce regulate inflammatory response caused by incremental exercise. 
کلیدواژه‌های انگلیسی مقاله Fish oil supplement, Inflammation, IL -17, CRP, CPK.
نویسندگان مقاله حمید علیزاده | hamid alizadeh
exercise physiology department, mazandaran university, mazandaran, iran.

سازمان اصلی تایید شده: دانشگاه مازندران (Mazandaran university)

بهزاد بازگیر | behzad bazgir
exercise physiology research center, baqiyatallah university of medical science, tehran, iran.


فرهاد دریانوش | farhad daryanoosh
department of physical education, shiraz university, shiraz, iran.

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

مریم کوشکی | maryam koushki
department of physical education, shiraz university, shiraz, iran.

سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)

وحید سبحانی | vahid sobhani
exercise physiology research center, baqiyatallah university of medical sciences,tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (Baqiyatallah university of medical sciences)

نشانی اینترنتی http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-611&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده 1
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