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Iranian Journal of Blood and Cancer، جلد ۵، شماره ۳، صفحات ۸۷-۹۱
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Determining Serum Zinc Level in Children with Cancer before and 3 Months after Chemotherapy in Kerman Province, Iran
چکیده انگلیسی مقاله Introduction: Cancer and chemotherapy could decrease serum Zinc level. In this study, serum Zinc level was investigated at the beginning of cancer diagnosis and 3 months after chemotherapy in children with all types of cancer. Method: In this cross sectional study forty-five 1-15 year old children who were newly diagnosed cancer cases (leukemia, lymphoma and solid tumor) were evaluated. Patients with previous chronic disease were excluded from the study. Serum Zinc level was measured before and 3 months after chemotherapy by an atomic absorption spectrophotometer. The relationship between serum Zn level and malnutrition was also evaluated in both steps. Results: The mean serum Zn level was 37.26±45.02 μg/dl at the beginning of cancer diagnosis and 11.96±24.59 μg/ dl 3 months after chemotherapy (p-value=0.002), which showed a significant statistical reduction. There was no significant statistical difference in Zinc level between groups in regard to age, gender, place of resident and type of cancer. Conclusion: This study indicated that Zinc level was lower than normal before chemotherapy and further decrease was seen after chemotherapy in all types of cancer among participating patients. Therefore, it is recommended to add Zinc supplement to chemotherapy protocols especially for malnourished patients. Keywords: Children, cancer, Zinc, chemotherapy, malnutrition.
کلیدواژه‌های انگلیسی مقاله Children, cancer, Zinc, chemotherapy, malnutrition.
نویسندگان مقاله a نادری | a naderi
pediatric hematologist oncologist, department of pediatrics, kerman university of medical sciences, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

z فرهمندی نیا | z farahmandinia
pediatric hematologist oncologist, department of pediatrics, kerman university of medical sciences, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

z شهرکی قدیمی | z shahraki ghadimi
. pediatrician, department of pediatrics, kerman university of medical sciences, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

f دوستان | f doustan
nutritionist, member of medical center, kerman university of medical sciences, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

h شهرکی قدیم | h shahraki ghadim
department of clinical biochemistry, faculty of medicine, zahedan university of medical sciences, zahedan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

n مداحیان | n madahian
head nurse of hematology and oncology pediatrics ward, afzalipour hospital, kerman, iran.


m حیات بخش عباسی | m hayat bakhsh abbasi
student of microbiology research center for tropical and infection diseases, kerman university of medical sciences, ker

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

نشانی اینترنتی http://www.ijbc.ir/browse.php?a_code=A-10-1-35&slc_lang=en&sid=en
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