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Iranian Journal of Blood and Cancer، جلد ۴، شماره ۱، صفحات ۱-۵

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عنوان انگلیسی Serum Antioxidant Levels in Children with Beta-Thalassemia Major
چکیده انگلیسی مقاله Background: Thalassemia represents a serious health problem in Iran because of its heterogeneous frequency and the existing endogamy system. It is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. Materials and Methods: In this study, serum antioxidants including selenium (Se), zinc (Zn) and copper (Cu) were measured using atomic absorption spectrometry (AAS) in children with beta-thalassemia major (n=40) and compared with the control group (n=40). Results: There were significant differences in the values of Se, Zn and Cu between the two groups. Se and Zn levels were 41.78±22.87 μg/l and 61.70±13.25 μg/dl in thalassemia, but 108.63±25.79 μg/l and 114.72±23.70 μg/dl in healthy children. Meanwhile, Cu levels were 156.60±22.62 and 102.88±31.15 μg/dl among patients and controls, respectively. Conclusion: This study shows that Se, Zn and Cu may play a role in the pathogenesis of beta-thalassemia major. Key words: Beta-thalassemia, antioxidants, children
کلیدواژه‌های انگلیسی مقاله Beta-thalassemia, antioxidants, children

نویسندگان مقاله l فرزین | l farzin
environmental laboratory, nuclear science research school, nuclear science and technology research institute, atomic


f سجادی | f sajadi
environmental laboratory, nuclear science research school, nuclear science and technology research institute, atomic


l kupai | l kupai
environmental laboratory, nuclear science research school, nuclear science and technology research institute, atomic



نشانی اینترنتی http://www.ijbc.ir/browse.php?a_code=A-10-9-9&slc_lang=en&sid=en
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